Lung Cancer Clinical Trial
Official title:
Molecular Predictors of Lung Cancer Behavior: Controls
RATIONALE: Studying samples of blood, urine, sputum, mouth cells, and bronchial tissue from
healthy participants in the laboratory may help doctors learn more about changes that occur
in DNA and identify biomarkers related to cancer. It may also help doctors learn more about
the development of cancer.
PURPOSE: This laboratory study is looking for molecular markers in predicting lung cancer
development using tissue samples from healthy participants.
OBJECTIVES:
- To obtain biological specimens from healthy participants with no known risk of lung
cancer to use as controls in the study of lung cancer progression.
- To identify new molecular abnormalities specific to the development of squamous cell
carcinoma of the lung.
OUTLINE: Serum, urine, sputum, and buccal cell samples are collected. Patients also undergo
bronchoscopy for collection of bronchial tissue and bronchial brush samples. The samples are
used for genomic and proteomic studies to identify new molecular abnormalities specific to
the development of lung cancer.
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Observational Model: Cohort, Time Perspective: Prospective
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