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Lung Cancer clinical trials

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NCT ID: NCT04166240 Active, not recruiting - Breast Cancer Clinical Trials

Measuring and Improving the Safety of Test Result Follow-Up

Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Improving communication is foundational to improving patient safety. Electronic health records (EHRs) can improve communication, but also introduce unique vulnerabilities. Failure to follow-up abnormal test results (missed results) is a key preventable factor in diagnosis and treatment delays in the VHA and often involves EHR-based communication breakdowns. Effective methods are needed to detect diagnostic delays and intervene appropriately. Manual techniques to detect care delays, such as spontaneous reporting and random chart reviews, have limited effectiveness, due in part to bias and lack of provider awareness of delays. They are also inefficient and cost-prohibitive when applied to large numbers of patients. Diagnostic errors are considered harder to tackle, in part because they are difficult to measure. Rigorous measurement of diagnostic safety is essential and should be prioritized given the increasing amount of electronically available data. To create an effective measurement and learning program researchers must (1) ensure teams know how to take actionable steps on data and have assistance in doing so and (2) prioritize diagnostic safety at the organizational level by securing commitment from local VA leadership and clinical operations personnel. This will ensure that safety measurement will translate into action. The proposed study focuses on creating a novel program to develop and evaluate multifaceted socio-technical tools and strategies to help prevent, detect, mitigate, and ameliorate breakdowns in EHR-based communication that often lead to "missed" test results in the VHA.

NCT ID: NCT04160143 Recruiting - Lung Cancer Clinical Trials

Post SBRT Pulmonary Metastasectomy (PSPM) Trial

PSPM
Start date: July 14, 2020
Phase: N/A
Study type: Interventional

The goal of this study is to determine the effectiveness of SBRT on reducing tumor viability at a pathologic level and also to evaluate the effects of combined modality treatment on low volume pulmonary metastases, in hopes of extrapolating this information to both primary and secondary lung cancer.

NCT ID: NCT04155008 Terminated - Lung Cancer Clinical Trials

Nutrition and Pharmacological Algorithm for Oncology Patients Study

Start date: March 1, 2021
Phase: Phase 4
Study type: Interventional

Loss of appetite is a common symptom of patients with cancer and can cause distress which impacts patients and caregivers. Patients diagnosed with head/neck, lung or pancreatic cancer will be recruited for this study to decrease the suffering and distress associated with eating during cancer treatment and improve the quality of life of patients by implementing an algorithm utilizing nutrition intervention and appetite stimulants.

NCT ID: NCT04145570 Completed - Lung Cancer Clinical Trials

A Single-Dose,ComparativeBioavailability Study ofTwo Formulations ofErlotinib150mgTabletsunderFastingConditions

Start date: October 23, 2008
Phase: Phase 4
Study type: Interventional

Theobjectiveofthisstudyistoevaluatethecomparativebioavailabilitybetween: - ErlotinibHCl150mgTablets(Novopharm Limited,Canada)and - Tarceva® 150mgTablets(Hoffmann-LaRocheLimited,Canada) afterasingle-doseinhealthysubjectsunderfastingconditions.

NCT ID: NCT04140474 Terminated - Lung Cancer Clinical Trials

Evaluation of the Archimedes ™ System for Transparenchymatous Access to Pulmonary Nodules.

SATAN
Start date: January 21, 2021
Phase: N/A
Study type: Interventional

The aim of this study protocol is to evaluate the feasibility of biopsies using the new system called Archimedes® in 12 patients with solitary pulmonary nodules (SPN) suspicious of malignancy not accessible through current bronchoscopy techniques.

NCT ID: NCT04139408 Completed - Lung Cancer Clinical Trials

Safety and Effectiveness of Disposable Pulmonary Surgical Markers in the Localization of Pulmonary Nodules

Start date: July 22, 2020
Phase: N/A
Study type: Interventional

During the VATS procedure, some pulmonary nodules are relatively small or far away from the pleura, resulting that they are difficult to be accurately located during the procedure. The aim of this study is to evaluate the efficacy and safety of using disposable pulmonary surgical markers to localize pulmonary nodules in subjects prior to the resection of pulmonary nodules by video-assisted thoracoscopic surgery (VATS).

NCT ID: NCT04131426 Completed - Lung Cancer Clinical Trials

Evaluating the Combined Intervention of Nutritional Supplementation (Remune) and Exercise in Patients With Cancer Cachexia

Start date: April 24, 2020
Phase: Phase 1
Study type: Interventional

The main purpose of this research study is to determine if the use of a nutritional supplement and exercise improve or worsen cachexia.

NCT ID: NCT04131231 Not yet recruiting - Breast Cancer Clinical Trials

Safety and Effectiveness of MPCD Therapy on the Treatment of Malignant Pleural Effusion

Start date: October 15, 2019
Phase: N/A
Study type: Interventional

This is a prospective, open-label , multicenter randomized controlled trial, with 248 cases in 50 centers planned for a period of 2 years. The aim of the study is to evaluate the safety and effectiveness of microparticles packaging chemotherapeutic drugs (MPCD) therapy on the treatment of malignant pleural effusion (MPE) in patients with advanced lung cancer or breast cancer.

NCT ID: NCT04119960 Completed - Lung Cancer Clinical Trials

Clinical Validation of InferRead Lung CT.AI

Start date: January 10, 2019
Phase:
Study type: Observational

Lung cancer is the second most common cause of cancer-related death in men and women. Early pulmonary nodule screening is an effective means to prevent lung cancer, which is no less important than the diagnosis and treatment of lung cancer. Early lung cancer screening has been investigated and applied as a medical practice. InferRead Lung CT.AI by Infervision is a dedicated post processing application that generates CADe marks as an overlay on the original CT series intended to aid the radiologist in the detection of pulmonary nodules. This study was designed to evaluate radiologists' performance in detecting actionable nodules on chest CT when aided by InferRead.

NCT ID: NCT04118660 Recruiting - Lung Cancer Clinical Trials

Thoracic Specimen Registry

Start date: March 1, 2017
Phase:
Study type: Observational [Patient Registry]

The purpose of the registry will be to support ongoing research in the etiology, early diagnosis, clinical management, and prognosis of lung cancer and other cancers and diseases of the thorax by developing a complete repository of specimens from patients with thoracic disease including but not limited to suspected lung cancer, mediastinal and pleural tumors, lung transplants and from patients at a very high risk of developing other thoracic cancers or other thoracic diseases.