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Lung Cancer clinical trials

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NCT ID: NCT00754910 Completed - Lung Cancer Clinical Trials

Photodynamic Therapy Using Porfimer Sodium in Treating Patients With Non-Small Cell Lung Cancer And Bronchial Disease

Start date: December 2008
Phase:
Study type: Observational

RATIONALE: Photodynamic therapy uses a drug that becomes active when it is exposed to a certain kind of light. When the drug is active, cancer cells are killed. This may be effective against non-small cell lung cancer. PURPOSE: This clinical trial is studying how well photodynamic therapy using porfimer sodium works in treating patients with non-small cell lung cancer and bronchial disease.

NCT ID: NCT00754858 Completed - Lung Cancer Clinical Trials

Belotecan and Cisplatin in Treating Patients With Previously Untreated, Extensive-Stage Small Cell Lung Cancer

Start date: October 2008
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Belotecan may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving belotecan together with cisplatin may kill more tumor cells. PURPOSE: This phase II trial is studying how well belotecan works when given together with cisplatin in treating patients with previously untreated extensive stage small cell lung cancer.

NCT ID: NCT00751660 Active, not recruiting - Lung Cancer Clinical Trials

Screening Methods in Finding Lung Cancer Early in Current or Former Smokers

Pan Can
Start date: September 2008
Phase: N/A
Study type: Interventional

RATIONALE: Screening may help doctors find lung cancer sooner, when it may be easier to treat. PURPOSE: This clinical trial is studying screening methods to see how well they find lung cancer early in current or former smokers.

NCT ID: NCT00750269 Completed - Lung Cancer Clinical Trials

Stereotactic Body Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer

Start date: February 2009
Phase: Phase 1/Phase 2
Study type: Interventional

RATIONALE: Stereotactic body radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue. PURPOSE: This phase I/II trial is studying the side effects and best dose of stereotactic body radiation therapy and to see how well it works in treating patients with stage I non-small cell lung cancer.

NCT ID: NCT00748163 Withdrawn - Lung Cancer Clinical Trials

Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Sunitinib as First-Line Therapy in Treating Patients With Stage IV Non-Small Cell Lung Cancer

Start date: August 2008
Phase: Phase 2
Study type: Interventional

RATIONALE: Drugs used in chemotherapy, such as paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Sunitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving paclitaxel albumin-stabilized nanoparticle formulation together with sunitinib may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving paclitaxel albumin-stabilized nanoparticle formulation together with sunitinib works as first-line therapy in treating patients with stage IV non-small cell lung cancer.

NCT ID: NCT00748085 Terminated - Lung Cancer Clinical Trials

CryoSpray Ablation(tm)in Malignant Airway Disease to Determine Safety, and Tissue Effect in the Lung (ICE the MAD)

ICEtheMAD
Start date: October 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety, and tissue effect of the CryoSpray Ablation(TM) System (CryoSpray Ablation(TM), "CSA" or "cryospray therapy") at multiple centers to treat malignant airway disease in the lung using liquid nitrogen sprayed through a catheter via flexible fiber optic bronchoscopy (FFB)

NCT ID: NCT00747773 Completed - Lung Cancer Clinical Trials

Cryospray Ablation of Surgical Resection Specimens To Determine Safety And Histological Effect In The Lung

CSAir 1
Start date: November 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the feasibility and general safety in the human airway as well as assess the safety and depth and area of treatment using liquid nitrogen sprayed through a catheter via flexible fiber optic bronchoscopy (FFB) using surgical resection specimens from patients undergoing lobectomy.

NCT ID: NCT00746759 Completed - Lung Cancer Clinical Trials

Airway Epithelium Gene Expression: AEGIS IDE

AEGIS IDE
Start date: February 2010
Phase: N/A
Study type: Observational

The purpose of the research study is to develop a new, more sensitive, and less invasive test for diagnosing lung cancer at an earlier stage, when it can more easily be cured. The investigators hypothesize that certain genes are expressed differently in current and former smokers who have lung cancer, and this difference in gene expression may be a biomarker for lung cancer.

NCT ID: NCT00745875 Completed - Lung Cancer Clinical Trials

ZD4054 (Zibotentan) Phase II Non-Small Cell Lung Cancer Study

Start date: August 2008
Phase: Phase 2
Study type: Interventional

The aim of this study is to collect initial efficacy and safety data on the use of a new treatment ZD4054 (Zibotentan) when used in combination with pemetrexed (a standard chemotherapy agent) for the treatment of non-small cell lung cancer compared to treatment with pemetrexed alone

NCT ID: NCT00745160 Completed - Lung Cancer Clinical Trials

Survey and Blood Sample Collection for Patients With Lung Cancer Who Never Smoked Cigarettes

Start date: August 2008
Phase: N/A
Study type: Observational

The purpose of this study is to determine if collecting information and blood from a group of people who never smoked but who have lung cancer, is possible across the US. The investigators will collect information on each patient's diagnosis and treatments. If the collection is successful, blood samples will be used to try to identify new genes (which are the basic elements of heredity, passed from parents to their offspring), which may explain and predict why certain patients develop lung cancer without having smoked tobacco.