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Clinical Trial Summary

The single arm clinical study is to evaluate the efficacy and safety of Tislelizumab combined with Bevacizumab and albumin paclitaxel in the treatment of advanced lung adenocarcinoma. All of the patients were received EGFR-TKI therapy for 1 line and disease progression. The primary endpoint is six months PFS and safety, the seconday endpoint is ORR and one-year OS rate.


Clinical Trial Description

Patients who meet the inclusion criteria will receive Tislelizumab combined with Bevacizumab and albumin paclitaxel for 4 cycles. If there is no disease progression, the patient will continue to receive Tislelizumab maintenance therapy, until the disease progresses or death. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04310943
Study type Interventional
Source Guangzhou Institute of Respiratory Disease
Contact
Status Completed
Phase Phase 2
Start date March 1, 2021
Completion date December 1, 2023

See also
  Status Clinical Trial Phase
Recruiting NCT05503667 - Neoadjuvant Furmonertinib Plus Bevacizumab or Furmonertinib Monotherapy for Resectable and Potentially Resectable Stage III-IVA EGFR Mutation-Positive Lung Adenocarcinoma Phase 2