Lumbar Spinal Stenosis Clinical Trial
Official title:
Dexamethasone as Adjuvant to Ropivacaine in Wound Infiltration for Postoperative Analgesia Following Spinal Surgery: A Randomized, Double-Blinded, Controlled Trial
Introduction: Improving postoperative pain management after spinal surgery is a significant challenge for surgeons and anesthesiologists. Pain following spinal surgery, can lead to significant morbidity, limit early mobility, and increase the risk of chronic pain. This trial examines the analgesic effects of dexamethasone as an adjuvant to ropivacaine in wound infiltration after lumbar surgery. Methods: In this study, we randomly assigned sixty patients undergoing lumbar laminectomy and/or osteosynthesis into two groups of 30 patients each. The control group (R-group) received only Ropivacaine (150 mg of Ropivacaine 7.5% (20 ml) added to 2 ml of normal saline in the wound infiltration), while the intervention group (RD-group) received Ropivacaine with the addition of dexamethasone (150 mg of Ropivacaine 7.5% (20 ml) added to 8 mg of dexamethasone in the wound infiltration). Both groups were administered patient-controlled analgesia (PCA) with morphine for self-medication. Postoperatively, a blinded evaluator assessed pain at H0, recorded the assessment of surgical scar pain using the Visual Analog Scale (VAS) at 4, 6, 12, 24, and 48 hours, as well as the time to the first opioid request, cumulative morphine consumption, opioid-related side effects, and length of stay. All patients were scheduled for a 3-month follow-up call to monitor chronic pain progression.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04795284 -
Biomechanical Parameters of Gait in Patients With Symptomatic Lumbar Spinal Stenosis and Healthy Elderly.
|
||
| Recruiting |
NCT04066296 -
Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine
|
Phase 2 | |
| Active, not recruiting |
NCT05114135 -
TLIF Osteo3 ZP Putty Study (Also Known as the TOP Fusion Study)
|
N/A | |
| Recruiting |
NCT06057428 -
Activity Levels Amongst Patients With Lumbar Spinal Stenosis
|
||
| Recruiting |
NCT06075862 -
Balance Amongst Patients With Lumbar Spinal Stenosis
|
||
| Recruiting |
NCT05527145 -
Spinal Stenosis and Listhesis Treated With Percutaneous Interspinous Spacer: a Non-surgical Trial
|
N/A | |
| Recruiting |
NCT01902979 -
The Spinal Stenosis Pedometer and Nutrition e-Health Lifestyle Intervention (SSPANLI) Trial
|
N/A | |
| Completed |
NCT00749073 -
The Vertos MILD™ Preliminary Patient Evaluation Study
|
N/A | |
| Completed |
NCT00527527 -
Chiropractic Dosage for Lumbar Stenosis
|
Phase 2 | |
| Completed |
NCT00405691 -
Safety and Effectiveness Study of the TOPS System, a Total Posterior Arthroplasty Implant Designed to Alleviate Pain Resulting From Moderate to Severe Lumbar Stenosis
|
Phase 3 | |
| Completed |
NCT03194607 -
Quantitative Evaluation of Motor Function Before and After Surgery for Degenerative Lumbar Spinal Stenosis
|
||
| Recruiting |
NCT06034405 -
Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis
|
||
| Completed |
NCT06079580 -
Patients With Lumbar Spinal Stenosis With Balance Disorder
|
||
| Recruiting |
NCT05523388 -
Role of Spinal Load in the Pathophysiology of Lumbar Spinal Stenosis
|
||
| Completed |
NCT04587401 -
The Effects of Anesthesia on Cerebral Perfusion in Patients With High Blood Pressure
|
N/A | |
| Completed |
NCT04563793 -
Postmarket Outcomes Study for Evaluation of the Superion™ Spacer
|
||
| Suspended |
NCT03381677 -
Pedicle Osteotomy for Stenosis Trial
|
N/A | |
| Completed |
NCT02258672 -
Preoperative Rehabilitation for Patients Undergoing Surgery for Lumbar Spinal Stenosis
|
N/A | |
| Completed |
NCT02260401 -
Long Term Outcomes of Lumbar Epidural Steroid Injections for Spinal Stenosis
|
N/A | |
| Completed |
NCT00401518 -
A Pivotal Study of a Facet Replacement System to Treat Spinal Stenosis
|
N/A |