Lower Gastrointestinal Bleeding Clinical Trial
Official title:
Role of MSCT Angiography in Evaluation of Lower Gastrointestinal Bleeding
Lower gastrointestinal bleeding occurs distal to the ligament of treitz and may involve the
small bowel, colon and rectum .
Active lower gastrointestinal bleeding is a common, potentially life threatening medical
presentation that can be challenging to localize and treat .
There are many diseases that may cause lower gastrointestinal bleeding, including
angiodysplasia, diverticulosis, benign or malignant bowel neoplasm, inflammatory bowel
disease, ischemic bowel disease, and infectious bowel disease.
Often, gastrointestinal bleeding will stop spontaneously, but in approximately 25% of
patients, bleeding is massive or recurrent, requiring imaging localization and directed
therapy.
Accurate and prompt diagnosis of the bleeding source is crucial because mortality can be as
high as 40%if there is hemodynamic instability in patients .
Because of the length of GI tract, the multitude of pathologic processes that can result in
GI bleeding, imaging plays a primary role in the diagnosis .
Multislice CT angiography (MSCTA) provides a relatively non-invasive and effective way of
localising the source of bleeding, especially in patients with continuous bleeding .
MSCTA is being increasingly used because it is a widely available, non-invasive and fast
diagnostic technique that allows for the visualization of the entire intestinal tract and its
lesions, the identification of the vascularity and possible vascular abnormalities. In
addition, this technique does not require preparation in patients with acute bleeding.
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| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03935360 -
Oakland-Jairath Score Validation
|
||
| Terminated |
NCT04729946 -
Clinical and Urgent Colonoscopy Outcomes Using the Pure-Vu® Cleansing System
|
N/A |