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Transanal Irrigation to Prevent Major Low Anterior Resection Syndrome — TAILARS  

Low Anterior Resection Syndrome Clinical Trial

Official title:
A Prospective, Randomized, Open, Parallel Trial of Transanal Irrigation to Prevent Major Low Anterior Resection Syndrome in Rectal Cancer Patients

Clinical Trial Summary

Bowel dysfunction after rectal cancer resection comprises a vast array of bowel symptoms and associated quality-of-life impairment, collectively termed as low anterior resection syndrome (LARS). There are 40%-60% patients who suffer from major LARS after sphincter-preserving surgery. No consensus exists for LARS treatment or prevention. Transanal irrigation (TAI) was reported to play a helpful role in the management of major LARS and fecal incontinence. However, the preventive effect and daily accessibility need further confirmation. In this randomized trial, TAI compared with best support treatment, is used in patients who received curative low anterior resection for rectal cancer with diverting stoma, after completion of the stoma reversal. The primary outcome is the occurrence of major LARS after 6 months of the treatment.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04758195
Study type Interventional
Source Sixth Affiliated Hospital, Sun Yat-sen University
Contact Qiyuan Qin, M.D.
Phone 86-20-38254052
Email qinqy3@mail.sysu.edu.cn
Status Recruiting
Phase N/A
Start date March 1, 2021
Completion date June 30, 2024
View Details
See also
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