Effect of TCI Propofol on Liver Transplant (TCI) Propofol on Intra-operative Usage of Vasopressors in Liver Transplant Recipients.

Liver Transplant Recipients Clinical Trial

Official title:
Effect of Isoflurane and Target Control Infusion (TCI) Propofol on Intra-operative Usage of Vasopressors in Liver Transplant Recipients: A Randomized Controlled Trial.

Status Recruiting

Clinical Trial Summary

Both isoflurane and propofol are being used to give anaesthesia for living donor liver transplant in our institute. Propofol when compared to isoflurane has advantages like early awakening from anaesthesia, reduced nausea, vomiting in the postoperative period. Propofol also has antioxidant properties. Because of its antioxidant properties propofol may have a protective effect against oxidative stress and ischemia reperfusion injury in major organs during liver transplant surgery. However, there are no studies showing the effect of isoflurane and propofol on Intraoperative hemodynamics and postoperative liver and kidney functions.Thus, we are conducting this study to know the effect of these agents on intraoperative hemodynamics and postoperative liver and kidney function.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Liver Transplant Recipients

Clinical Trial Details

NCT number	NCT06418893
Study type	Interventional
Source	Institute of Liver and Biliary Sciences, India
Contact	Abhinav Sharma, MD
Phone	8860790151
Email	abhi27sh@gmail.com
Status	Recruiting
Phase	Phase 2/Phase 3
Start date	August 1, 2023
Completion date	October 31, 2024

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT01525797` - Blood Draw Study for Liver Transplant Patients	N/A
Completed	`NCT00587418` - L-arginine for Prevention of Kidney Damage in Liver Transplant Recipients	N/A
Completed	`NCT01889758` - Pharmacokinetic Studies of Tacrolimus in Transplant Patients	Phase 4
Completed	`NCT02482974` - Conversion From Sirolimus to Everolimus in the Maintenance Treatment of Liver Transplant Recipients	N/A
Completed	`NCT02320422` - Adult Liver Transplant Enhanced Care	N/A
Active, not recruiting	`NCT05077254` - COVID Protection After Transplant-Immunosuppression Reduction	Phase 2
Completed	`NCT00275639` - The Effects of Angiotensin II Receptor Blockade on Kidney Function and Scarring After Liver Transplant	Phase 4
Completed	`NCT01672164` - Discovery and Validation of Proteogenomic Biomarker Panels in Liver Transplant Recipients	N/A
Completed	`NCT01638559` - Immunosuppression Withdrawal for Stable Pediatric Liver Transplant Recipients	Phase 2