Precise Evaluation Criteria for Histological Regression of NASH Fibrosis

Status Not yet recruiting

Clinical Trial Summary

It is an observational study of NASH patients with a calculated sample size of 220. Liver biopsy-proven NASH fibrosis with stage F2-F4 will be recruited in this study. A second biopsy will be performed after clinical trials or 1-3 years of lifestyle intervention. Patients will be followed up at baseline and every six months with h-CRP, liver function tests, fasting blood glucose, fasting insulin, ferritin, liver ultrasonography, and liver stiffness measurements.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06364462
Study type	Observational [Patient Registry]
Source	Beijing Friendship Hospital
Contact	Yameng Sun, M.D.
Phone	86-010-63138656
Email	sunyamenggo@163.com
Status	Not yet recruiting
Phase
Start date	May 1, 2024
Completion date	April 1, 2027

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06308757` - Role of the Very Low Calorie Ketogenic Diet (VLCKD) in Patients With Non-Alcoholic Steatohepatitis (NASH) With Fibrosis	N/A
Recruiting	`NCT06051669` - Comparison of iLivTouch and FibroScan for the Assessment of Liver Fibrosis and Steatosis in Adult Patients in the US
Completed	`NCT06244550` - Clinical Trials Using HepatoKeeper Herbal Essentials to Treat Non-alcoholic Fatty Liver Disease and Metabolic Factors	N/A
Recruiting	`NCT06098417` - Biomarkers in the Diagnosis and Prognosis of NAFLD
Not yet recruiting	`NCT03623360` - Functional MRI to Determine Severity of Cirrhosis
Recruiting	`NCT01965418` - A Clinical Evaluation on Traditional Chinese Medicine Diagnosis and Treatment Program Blocking and Reversing Hepatitis B-related Liver Fibrosis - a Randomized, Controlled, Double-blind, Multi-center Clinical Trial	Phase 4
Not yet recruiting	`NCT01133184` - Improved Prevention of Perinatal Hepatitis B Transmission	Phase 4
Completed	`NCT00043303` - Safety and Efficacy Study of Interferon Gamma-1b in Hepatitis C Patients With Liver Fibrosis or Cirrhosis	Phase 2
Completed	`NCT03872024` - Performances Evaluation of New FibroScan Probes Dedicated to Morbidly Obese Patients	N/A
Recruiting	`NCT05912179` - Prospective Single Centre Observational Study to Compare the Diagnostic Yield of Different Modalities of Liver Biopsy
Recruiting	`NCT04533828` - 68Ga-FAPI PET/CT in Liver Fibrosis Patients	Early Phase 1
Completed	`NCT04573543` - The Role of Immune Semaphorins in NAFLD
Recruiting	`NCT03277651` - Noninvasive Diagnostic Platform for Liver Fibrosis and Portal Hypertension	N/A
Completed	`NCT01707472` - Study of Simtuzumab in HIV and/or Hepatitis C- Infected Adults With Liver Fibrosis	Phase 2
Not yet recruiting	`NCT05935488` - Early Liver Disease Breath Detection
Completed	`NCT01988753` - Non-invasive Biomarkers of Fibrosis in Pediatric Liver Diseases
Completed	`NCT01934777` - Efficacy and Tolerance of Treatment With DHA, Choline and Vitamin E in Children With Non-alcoholic Steatohepatitis	Phase 3
Completed	`NCT01810458` - Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)
Completed	`NCT02060162` - Antiretroviral Treatment Outcomes in HIV-HBV Co-infected Patients in Southern Africa
Completed	`NCT00049842` - Prevention of Disease Progress in Chronic Hepatitis C Patients With Liver Fibrosis (Study P02570AM2)(COMPLETED)	Phase 3