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Liver Cirrhosis clinical trials

View clinical trials related to Liver Cirrhosis.

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NCT ID: NCT02473601 Recruiting - Liver Dysfunction Clinical Trials

Mivacurium Chloramine Muscle Relaxation Effect in Patients With Liver Cirrhosis

Start date: October 2014
Phase: Phase 2
Study type: Interventional

Observed the muscle relaxation of mivacurium in patients with liver cirrhosis.Clear of mivacurium in patients with liver cirrhosis without muscle relaxant accumulation and delayed recovery phenomenon

NCT ID: NCT02470546 Recruiting - Liver Cirrhosis Clinical Trials

Metformin Experience on Minimal Hepatic Encephalopathy

EME
Start date: March 2015
Phase: Phase 4
Study type: Interventional

Primary aim: -To assess the effect of metformin use on the treatment of minimal hepatic encephalopathy in patients with liver cirrhosis. Secondary aim: -To evaluate if metformin is a safety drug in patients showing liver cirrhosis.

NCT ID: NCT02427906 Recruiting - Cirrhosis Clinical Trials

Effect of Transjugular Intrahepatic Portosystemic Shunt on Gut Microbiota in Cirrhotic Patients

Start date: August 2014
Phase: N/A
Study type: Observational [Patient Registry]

The purpose of this study is to determine the effect of transjugular intrahepatic portosystemic shunt on gut microbiota and associated inflammatory factors in cirrhotic patients.

NCT ID: NCT02423395 Recruiting - Liver Cirrhosis Clinical Trials

Study of Orphenadrine` in the Treatment of Muscle Cramps in Patients With Cirrhosis

Start date: January 2015
Phase: Phase 3
Study type: Interventional

Muscle cramps are common in patients with liver disease and associated with significantly diminished quality of life. Patients with cirrhosis often experience muscle cramps with varied frequency and severity. The exact mechanisms by which they occur remain unclear, although a number of pathophysiological events unique to liver disease may contribute. Clinical studies have identified alterations in 3 areas: nerve function, energy metabolism, and plasma volume/electrolytes (1) Orphenadrine is an anticholinergic drug with prominent central nervous system (CNS) and peripheral actions used to treat painful muscle spasms and other similar conditions. The combination of anticholinergic effects and CNS penetration make orphenadrine useful for pain of all etiologies, including from: radiculopathy, muscles, and headaches. [3,4]

NCT ID: NCT02415348 Recruiting - Liver Cirrhosis Clinical Trials

The Use of Fibroscan to Assess Liver Fibrosis in Patients With Cardiac Pacemakers

Start date: April 2015
Phase: N/A
Study type: Interventional

This study is designed to determine if the Fibroscan (Echosens, Paris), a non-invasive, ultrasound-based device used to estimate fibrosis in patients with chronic liver disease, interferes with implanted cardiac pacemaker and/or implantable cardioverter-defibrillators. Recruitment consists of a total of 200 outpatients undergoing routine pacemaker interrogation at a teaching-hospital pacemaker clinic.

NCT ID: NCT02407769 Recruiting - Liver Cirrhosis Clinical Trials

Late Evening Supplementation With Branched Chain Amino Acids in Liver Transplantation

Start date: February 2014
Phase: N/A
Study type: Interventional

Assess the impact in body composition and handgrip strength of the nocturne supplementation by a month with BCAA (Enterex hepatic in patients awaiting liver transplantation)

NCT ID: NCT02405416 Recruiting - Liver Cirrhosis Clinical Trials

Infrahepatic Inferior Vena Cava Clamping Versus Selective Hepatic Vascular Exclusion Involving the Portal Triad Clamping

Start date: March 2015
Phase: N/A
Study type: Interventional

This clinical trial aims to compare infrahepatic inferior vena cava clamping (IIVCC) with selective hepatic vascular exclusion (SHVE) involving the portal triad clamping (PTC) in complex cirrhotic liver resection. One group will receive IIVCC plus PTC, while an another equivalent group patients will be operated using SHVE and PTC.

NCT ID: NCT02401490 Recruiting - Cirrhosis Clinical Trials

Albumin Infusion Effects in Mortality in Patients With Cirrhosis and Hepatic Encephalopathy

BETA
Start date: April 2015
Phase: Phase 4
Study type: Interventional

To assess whether albumin administration after an episode of hepatic encephalopathy (≥ grade II) improves survival at 90 days (mortality endpoint treated as a composite endpoint death and/ or liver transplantation).

NCT ID: NCT02398357 Recruiting - Liver Cirrhosis Clinical Trials

The Effect of Anticoagulation After Endoscopic Therapy in Cirrhotic Patients With Portal Vein Thrombosis

Start date: March 2015
Phase: Phase 4
Study type: Interventional

To determine the effect and safety of anticoagulation after endoscopic therapy in cirrhotic patients with portal vein thrombosis and to explore whether it can decrease the short-term rebleeding rate.

NCT ID: NCT02385422 Recruiting - Liver Cirrhosis Clinical Trials

The Effect of Carvedilol Vs Propranolol in Cirrhotic Patients With Variceal Bleeding

Start date: March 2015
Phase: Phase 4
Study type: Interventional

To compare the efficacy and safety of Carvedilol and Propranolol in patients with cirrhosis-related esophagogastric varices after multiple endoscopic treatments for secondary prophylaxis.