Leukemia Clinical Trial
Official title:
Evaluation of Mer and Axl Expression in Acute Myeloid Leukemia Patient Samples
RATIONALE: Studying samples of blood and tissue from patients with cancer in the laboratory
may help doctors learn more about changes that occur in DNA and identify biomarkers related
to cancer.
PURPOSE: This research study is studying blood and tumor tissue samples from young patients
with acute myeloid leukemia.
OBJECTIVES:
- To evaluate Mer and Axl expression in samples from pediatric patients with acute
myeloid leukemia (AML).
- To determine if abnormal expression of Mer and Axl is associated with poor clinical
characteristics (e.g., induction failure or relapse) of AML in these patients.
OUTLINE: This is a multicenter study.
Archived samples from pediatric patients with acute myeloid leukemia are analyzed for Mer
and Axl expression by flow cytometry and western blot assays.
;
Observational Model: Case-Only, Time Perspective: Retrospective
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