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Capecitabine, Tucatinib, and Intrathecal Trastuzumab for Breast Cancer Patients With Leptomeningeal Disease — ETIC-LM  

Leptomeningeal Metastasis Clinical Trial

Official title:
Multicentric Single Arm Phase II Study Evaluating the Efficacy of Association of Tucatinib, Capecitabine and Intra-CSF Trastuzumab in HER2 Amplified Breast Cancer Patients With Leptomeningeal Metastases

Clinical Trial Summary

The goal of this clinical trial is to evaluate the efficacy of tucatinib and capecitabine in combination with intrathecal trastuzumab on overall survival rate at 12 months in HER2-positive metastatic breast cancer (MBC) patients with proven leptomeningeal evolution and requiring intrathecal therapy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05800275
Study type Interventional
Source UNICANCER
Contact Telma ROQUE, PhD
Phone +33 (0) 1 80 50 12 92
Email t-roque@unicancer.fr
Status Recruiting
Phase Phase 2
Start date December 18, 2023
Completion date June 2027
View Details
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