Larynx Cancer Clinical Trial
Official title:
High Resolution MRI in the Evaluation of Laryngeal Neoplasia
Verified date | October 2017 |
Source | Stanford University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
To determine if high resolution MRI can detect early invasion of cartilage by laryngeal carcinoma, and to determine if high resolution MRI may be superior to conventional MRI imaging or CT imaging to detect cartilage invasion.
Status | Terminated |
Enrollment | 3 |
Est. completion date | January 2010 |
Est. primary completion date | January 2010 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Patients with benign or malignant neoplasm of the larynx. - Patients who have undergone prior surgery, radiation therapy, or chemotherapy for cancer of the laryngopharynx will be eligible to participate. - Patients 18 years of age and older at time of evaluation, male and female, all ethnicities. - Ability to understand and the willingness to sign a written informed consent document. Exclusion Criteria: - Pregnancy - Claustrophobia. - Anatomic parameters which preclude scanning, such as limited range of neck motion, or inability to remain flat for at least 15 minutes. - Patients with implanted devices (eg, defibrillator, pacemaker) that are a known contraindication to magnetic resonance imaging. - Allergy to gadolinium contrast. |
Country | Name | City | State |
---|---|---|---|
United States | Stanford University School of Medicine | Stanford | California |
Lead Sponsor | Collaborator |
---|---|
Stanford University |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Tumor stage as determined by HRMRI. | Radiologic tumor stage | 24 to 48 hours | |
Secondary | Estimate the precision of HRMRI in discriminating between edema and tumor in patients with prior radiotherapy or chemotherapy. | Comparison of true tumor dimension as predicted by HRMRI versus true tumor size as shown on final histopathology | 4 to 6 weeks | |
Secondary | Tumor stage as determined by histopathology in excised larynges. | Pathological tumor stage | 4 to 6 weeks |
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