Clinical Trials Logo

Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT01719796
Other study ID # KTAP
Secondary ID
Status Recruiting
Phase Phase 2
First received October 24, 2012
Last updated October 30, 2012
Start date October 2012
Est. completion date December 2014

Study information

Verified date October 2012
Source Pierre and Marie Curie University
Contact Mathieu RAUX, MD, PhD
Phone +33142177379
Email mathieu.raux@psl.aphp.fr
Is FDA regulated No
Health authority France: Drug Safety National Agency
Study type Interventional

Clinical Trial Summary

Abdominal surgery impairs ventilation. Postoperative pain accounts for this impairment. Regional analgesia is known to reduce pain, thus to limit ventilatory impairment. The investigators hypothesized bilateral continuous transverse abdominal plan block would reduce ventilatory impairment following abdominal surgery.


Recruitment information / eligibility

Status Recruiting
Enrollment 60
Est. completion date December 2014
Est. primary completion date December 2014
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- laparotomy

Exclusion Criteria:

- below 18, pregnancy, prisoners

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


Intervention

Procedure:
Regional analgesia infusion


Locations

Country Name City State
France Centre Hospitalier Universitaire de Nîmes Nîmes
France Centre Hospitalier Universitaire de Saint-Etienne Saint-Etienne

Sponsors (1)

Lead Sponsor Collaborator
Pierre and Marie Curie University

Country where clinical trial is conducted

France, 

Outcome

Type Measure Description Time frame Safety issue
Primary vital capacity 72h No
Secondary maximum forced expiratory flow 72h No
Secondary analgesic consumption 72h No
Secondary pain resting pain, assessed using VAS 72h No
Secondary diaphragmatic course using ultrasonography 72h No
See also
  Status Clinical Trial Phase
Enrolling by invitation NCT03234543 - Remote Ischemic Conditioning in Abdominal Surgery N/A
Completed NCT03827291 - QL Block With Exparel in Colectomy Phase 4
Completed NCT02596269 - Nefopam/Fentanyl Postoperative Intravenous Patient-Controlled-Analgesia Phase 2/Phase 3
Completed NCT00364741 - Supplemental Oxygen and Complications After Abdominal Surgery (The PROXI-trial) Phase 4
Completed NCT01723280 - Supplemental Oxygen - Effect on Occurrence of Subsequent Cancer After Abdominal Surgery (Follow-up of the PROXI Trial) N/A
Terminated NCT00514566 - PDS vs Polyamide for Midline Abdominal Closure N/A
Recruiting NCT06089551 - Early vs Postponed Parenteral Nutrition After Emergency Abdominal Surgery Phase 4
Withdrawn NCT03966768 - DuraMesh Laparotomy Study N/A
Recruiting NCT04985695 - Influence of Analgesic Technique on Post Operative Rehabilitation After Median Laparotomy N/A
Recruiting NCT03739944 - Different Surgical Approaches in Patients of Early-stage Cervical Cancer Phase 3
Terminated NCT01890408 - Continuous Preperitoneal Infusion of Ropivacaine After Open Liver Resection: Effect on Post-operative Recovery and Morbidity. Phase 2
Recruiting NCT00544583 - Continuous Versus Interrupted Abdominal Wall Closure After Emergency Midline Laparotomy Phase 2/Phase 3
Recruiting NCT04256798 - Perioperative Respiratory Care and Outcomes for Patients Undergoing High Risk Abdominal Surgery Phase 3
Recruiting NCT03738969 - Longitudinal Study of Different Surgical Approaches in Chinese Patients of Uterine Cervical Cancer
Completed NCT03989570 - Transversus Abdominis Plane Block Versus Erector Spinae Plane Block N/A
Not yet recruiting NCT04266535 - TCI vs Manually Controlled Infusion of Propofol
Completed NCT04065607 - Indications and Outcome of Laparostomy
Completed NCT01040013 - Gut Oxygenation and Laparoscopy Phase 2
Completed NCT00637936 - Respiratory Effects of Perioperative Oxygen During General Anaesthesia Phase 4
Recruiting NCT03963882 - NAC Followed by RH for the Treatment of LACC Phase 2