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NCT06396351 Clinical Trial

Factors Affecting Abdominal Compliance During CO2 Insufflation in Laparoscopic Abdominal Surgery

Laparoscopic Surgery Clinical Trial

Official title:
Factors Influencing Abdominal Compliance During CO2 Insufflation in Patients Undergoing Laparoscopic Abdominal Surgery

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT06396351
Other study ID # I07-432-22
Secondary ID
Status Completed
Phase
First received
Last updated
Start date August 1, 2022
Est. completion date November 30, 2022

Study information
Verified date April 2024
Source Ankara University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The authors aimed to evaluate factors influencing abdominal compliance in laparoscopic abdominal surgery.

Description:

During laparoscopic surgery, pneumoperitoneum is achieved by insufflating carbon dioxide (CO2) gas into the abdominal cavity to create a safe working space. Pneumoperitoneum-induced elevation in intra-abdominal pressure (IAP) can result in various complications. Abdominal compliance (AC), represents the slope of the P-V curve of the abdominal cavity and is a measure of the ease of abdominal dilatation, is important to balance between surgical safety and complications. The aim of this study was to determine the effect of demographic and anatomic variables on AC. The study included 90 patients who underwent laparoscopic abdominal surgery. Subcutaneous adipose tissue and abdominal muscle thickness were measured ultrasonographically. Mean AC was calculated during insufflation using the formula (ΔV/ΔP). The relationship between demographic and anatomic variables and AC was investigated

Recruitment information / eligibility
Status Completed
Enrollment 90
Est. completion date November 30, 2022
Est. primary completion date November 30, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 82 Years
Eligibility Inclusion Criteria: Aged between 18 and 82 years ASA class I-III Elective abdominal surgery with laparoscopic technique - Exclusion Criteria: Aged below 18 and above 82 ASA IV-V

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Laparoscopic surgery
effect of carbondioxide insufflation on abdominal compliance was evaluated

Locations
Country Name City State
Turkey Ankara University Medical School Anesthesiology and ICU Department Ankara

Sponsors (1)
Lead Sponsor Collaborator
Ankara University

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary The factors affecting abdominal compliance Effect of rectus muscle thickness and lateral abdominal muscle group thickness on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation. From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Secondary The factors affecting abdominal compliance From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Secondary The factors affecting abdominal compliance Effect of age on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation. From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Secondary The factors affecting abdominal compliance Effect of gender on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation. From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Secondary The factors affecting abdominal compliance Effect of ASA physical status on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation. From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Secondary The factors affecting abdominal compliance Effect of body mass index on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation. From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Secondary The factors affecting abdominal compliance Effect of previous surgery on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation. From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Secondary The factors affecting abdominal compliance Effect of pregnancy on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation. From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
Secondary The factors affecting abdominal compliance Effect of subcutaneous adipose tissue thickness on abdominal compliance. Abdominal compliance is calculated by dividing intrabdominal volume change to intraabdominal pressure change during abdominal carbondioxide insufflation. From the beginning of carbondioxide insufflation to the intraabdominal pressure of 15 mmHg during surgery
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