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Labor Pain clinical trials

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NCT ID: NCT01555671 Completed - Labor Pain Clinical Trials

Study of the Effectiveness of Administration of Meperidine on the Length of Active Phase of Labor in Women

Start date: January 1, 2012
Phase: Phase 4
Study type: Interventional

This study aims to evaluate the effect of meperidine on the length of active phase of labor in nulliparous or multiparous women, who will be randomized into two (control and study) groups. Our hypothesis is that the use of meperidine during active labor has no effect on the duration of labor.

NCT ID: NCT01513447 Terminated - Labor Pain Clinical Trials

Intracutaneous Sterile Water Injections

Start date: December 2011
Phase: N/A
Study type: Interventional

For most women, the most significant pain they will experience is the pain associated with childbirth. Up to one-third of women experience "back labor", this typically occurs when the fetus assumes varying degrees of malposition, especially the occiput posterior position, and causes additional constant pressure against the maternal spine and pelvis. "Back labor" presents as constant pain, that occurs even between contractions. It is often difficult to manage, by the patient, the obstetrician, and the anesthesiologist, and may increase the rate of instrumental and caesarian delivery. Epidural anesthesia/analgesia is the most common and effective intervention used to help women cope with labor pain. Dilute concentrations of local anesthetic and opioid provide complete analgesia for most women. Some women, however, have breakthrough pain, often due to "back labor," and require more concentrated drug solutions. This increases the side effects associated with these drugs (e.g., hypotension, pruritus, motor block), thus treatment of this pain poses a challenge for the anesthesiologist and the obstetrician. Sterile water injections (SWI) are a simple and well-established method of managing labor pain among midwives. This intervention was first used to alleviate pain associated with kidney stones, and was introduced to obstetrics in the 1970s. Using a syringe, small amounts of sterile water is deposited subcutaneously near the sacral area. The sterile water causes osmotic and mechanical irritation resulting in a brief (15-30 second) and significant stinging sensation. The onset of pain relief follows almost immediately and may last for up to two hours. The procedure can be repeated a number of times. Sterile water for pain management is most often administered using four intracutaneous injections: two sites lateral to the lumbosacral spine and two sites 2-3 cm below and 1-2 cm medial to the original two injection sites. 0.1 mL of sterile water is injected between the dermal layers to raise a small bleb on the skin surface at each of the four sites. In labor, the injections are administered sequentially during a uterine contraction, with the series of four injections, performed two at a time, completed within 20-30 seconds. The investigators hypothesize that the use of sterile water injections in women with neuraxial analgesia with breakthrough pain will result in decreased local anesthetic requirements and increase patient satisfaction.

NCT ID: NCT01505283 Terminated - Labor Pain Clinical Trials

Effect of Epidural Analgesia on the Parameter ANI During Childbirth

APD-ANI
Start date: December 2011
Phase: N/A
Study type: Interventional

There are many methods used for the assessment of pain in the area of anesthesia including heart rate variability which reflects the influence of the autonomic nervous system on the heart. An original index, the ANI (Analgesia Nociception Index), quantifies pain during anesthesia. Obstetric epidural analgesia is particularly suited to evaluate ANI in conscious patients with a comparison of ANI with the measurement of pain by a visual analog scale (VAS). Evaluation of ANI is performed just before epidural catheter insertion and during the 10 first minutes after saline, sufentanil or lidocaine epidural administration.

NCT ID: NCT01428375 Completed - Labor Pain Clinical Trials

Intravenous Infusion of Paracetamol for Intrapartum Analgesia of Labor

Start date: August 2011
Phase: Phase 3
Study type: Interventional

This is a double-blind randomized trial evaluates the efficacy of intravenous infusion of Paracetamol as intrapartum analgesic in the first stage of labour.

NCT ID: NCT01394731 Completed - Labor Pain Clinical Trials

Analgesic Effects of Intravenous Paracetamol on Labor Pain

Start date: December 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether intravenous paracetamol is effective in treating labor pain.

NCT ID: NCT01389128 Completed - Labour Pain Clinical Trials

Non-pharmacological Resources in Assisting Labor

Start date: October 2011
Phase: N/A
Study type: Interventional

The proposed project will be conducted to evaluate the influence of application resources associated with non-pharmacological during labor for pain relief and accelerated phase of expansion. Although mothers' access to resources for non-pharmacological pain relief during labor is recommended, is not seen as the application of routine obstetric practice, although it has been demonstrated benefits and scientific evidence with your application. It is believed that the implementation of associated application of non-pharmacological resources in assisting the labor can be introduced into daily practice in various hospitals in the country, minimizing pain and favoring the shorter duration of labor, decrease in use of painkillers and inductors, resulting in a reduction of complications, improves the comfort of the mother making her birth experience more satisfying and rewarding, being assisted with security and trained by multidisciplinary teams.

NCT ID: NCT01243216 Withdrawn - Pregnancy Clinical Trials

Does Ultrasound of the Spine Improve Labor Epidurals/Spinal Anesthesia in Obstetric Patients?

Start date: October 2010
Phase: N/A
Study type: Interventional

The investigators are interested in determining the utility of ultrasound of the spine for labor epidurals or spinal anesthesia for women in labor or having a cesarean delivery. The investigators hypothesized that in women with poor spinal landmarks that the use of ultrasound of the spine will improve the process of placing labor epidurals or spinal anesthetics

NCT ID: NCT01205360 Withdrawn - Clinical trials for Primigravida in Labour Pains

Dosing Strategies for Automated Mandatory Intermittent Boluses Technique for Epidural Labour Analgesia

Start date: August 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how manipulation of the programmed intermittent time interval and volume influences total drug use, quality of analgesia, and patient satisfaction during maintenance of labor analgesia.

NCT ID: NCT01197950 Completed - Labour Pain Clinical Trials

Acupuncture With Manual and Electrical Stimulation to Reduce Labour Pain

Start date: October 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effect of manual acupuncture and electro-acupuncture on labour pain.

NCT ID: NCT01182220 Completed - Labor Pain Clinical Trials

Comparison of Ultrasound Guided Low Epidural Catheter Placement With Standard Epidural Catheter Placement

Start date: January 2013
Phase: N/A
Study type: Observational

1. labor epidural quite often require bolus supplementation for better pain control control. Quite often this is due to sparing of sacral nerves. 2. If epidural is placed low in the L5/S1 interspace using ultrasound, this may minimize bolus requirement and improve patient labor experience.