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Kwashiorkor clinical trials

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NCT ID: NCT03520621 Completed - Kwashiorkor Clinical Trials

The Role of Sulfur Amino Acids in Risk of Kwashiorkor

Start date: June 1, 2016
Phase:
Study type: Observational

This observational cross-sectional study is investigating if young children in populations with higher prevalence of kwashiorkor malnutrition have lower dietary sulfur amino acid intake than populations with lower prevalence of kwashiorkor, controlling for multiple potential confounding factors. Intake is estimated through diet recalls during interviews with a child's caregiver, analysis of urine samples and analysis of food samples for their amino acid profiles.

NCT ID: NCT03181178 Completed - Growth Disorders Clinical Trials

Effect of a Complementary Food Supplement on Growth and Morbidity of Ghanaian Infants

TRIUMF
Start date: February 2013
Phase: N/A
Study type: Interventional

Prevention of malnutrition in infants and children requires access and intake of nutritious food starting at birth with exclusive breastfeeding for the first 6 months of life, breastfeeding in combination with complementary foods from 6-24 months of age, access to clean drinking water and sanitation, access to preventive and curative health care (including prenatal). In Ghana, the Demographic and Health Survey of 2014 reports rates of stunting, wasting and underweight in children aged 0-59 months are 28%, 14% and 9% respectively. Furthermore, height for age starts dropping from age 4-6 months with children aged 6-23 months being more likely to be stunted (40%) than those below 6 months (4%). Infant and young child feeding data show that for breast-fed children ranging from 6 months through 35 months of age, cereals are predominantly the first foods introduced in the diet (6-8 months of age). As the child grows older, consumption of fruits rich in Vitamin A, other fruits and vegetables and meat, fish, poultry and eggs are reported by the mothers. The Demographic and Health Survey (DHS) found that the proportion of breast fed children aged 6-23 months who received a recommended variety of foods the minimum number of times per day increases with child's age from 28% in children 6-8 months to 50% in children aged 18-23 months. The study objective is to examine the effect of providing a macro- and micro-nutrient fortified complementary food supplement (KokoPlusTM) on growth and nutritional status of Ghanaian infants.

NCT ID: NCT03140696 Completed - Clinical trials for Protein Malnutrition

Formative Research Study to Address Protein Intake in Children and Analysis of Breast Milk Nutrient Content in Mothers

Start date: March 30, 2017
Phase: N/A
Study type: Interventional

This formative research seeks to explore the use of egg (as a potential source of protein) as nutritional supplement for young children aged 6-8 months of either sex and breast milk composition of mothers of infants under 6 months old living in an urban slum of Dhaka city, Bangladesh.

NCT ID: NCT03032237 Completed - Clinical trials for Malnutrition; Protein

Increase Protein Intake of Older Meal Service Clients With Readymade Protein-rich Meals and Foods

ConsuMEER
Start date: April 4, 2017
Phase: N/A
Study type: Interventional

Rationale: Undernutrition risk among community-dwelling older adults in developed countries is shown to be around 24%. Increasing protein intake is a strategy that is feasible as well as efficacious to reduce undernutrition in community-dwelling older adults. A promising strategy to increase protein intake among older adults, is to offer dietary solutions with normal foods that fit their current daily eating patterns. For this reason, home-delivered protein-rich readymade meals and protein-rich dairy products will be studied in this research. Objective: The primary objective is to study the effectiveness of commercially available protein-rich readymade meals and protein-rich dairy products in increasing protein intake of older adults who use a meal-delivery service to a level of 1.2 g/kg bodyweight/d. Secondary objectives include: studying effects of these meals and dairy products on total daily energy intake. Further, studying the acceptance of and compliance to the meals and dairy products. Study design: The study will be performed as a single-blind randomized, controlled, four-week trial in a real-life setting: in community-dwelling older adults' own homes. Study population: The target group of this study are community-dwelling older adults who use a meal-delivery service. Intervention: Both groups will receive readymade meals for each day during 4 weeks. They will also receive dairy products to freely consume during the intervention period. The intervention groups receives protein-rich meals and protein-rich dairy products, the control receives standard meals and food products. Main study parameters/endpoints: Difference in daily protein intake between intervention and control group. Secondary parameters: energy intake and acceptance (liking).

NCT ID: NCT02413905 Completed - Malnutrition Clinical Trials

Characterizing the Gut Microbiota Alteration Associated With Severe Acute Malnutrition

Start date: January 2014
Phase: N/A
Study type: Observational

The investigators performed two case-control studies in Niger and Senegal analysing fecal microbiota to characterize the specificity of the gut microbiota alteration associated with severe acute malnutrition (SAM).

NCT ID: NCT02053857 Completed - Kwashiorkor Clinical Trials

Pilot Study of PUFA-optimized RUTF for Severe Acute Malnutrition

Start date: February 2014
Phase: N/A
Study type: Interventional

To test whether a ready-to-use therapeutic food (RUTF) enriched with polyunsaturated fatty acids (RUTF-P) is as effective for the treatment of severe acute malnutrition (SAM) as standard RUTF.

NCT ID: NCT02001636 Completed - Clinical trials for Protein Malnutrition

Effect of Protein Supplementation After Bariatric Surgery

EPEAB
Start date: November 2011
Phase: N/A
Study type: Interventional

Obese patients, who underwent bariatric surgery, are at risk to develop protein malnutrition. The aim of this study is to evaluate the influence of postoperative protein supplementation on weight reduction, body composition and protein status.

NCT ID: NCT01790815 Completed - Malnutrition Clinical Trials

Mothers Understand And Can do it - Mid Upper Arm Circumference Screening for Malnutrition Performed by Mothers

MUAC
Start date: August 2011
Phase: N/A
Study type: Observational

PRIMARY OBJECTIVE : To determine whether mothers, given minimal group training, are capable of using a MUAC (mid-upper arm circumference) bracelet to screen their children for malnutrition and categorise them into one of three groups : 'red' (SAM ; severe acute malnutrition), 'yellow' (MAM ; moderate acute malnutrition) or 'green' (normal nutritional status) SECONDARY OBJECTIVES : To establish whether there is a difference in the MUAC value if measured on the right arm as opposed to the left, in young children To determine whether there is a difference in the MUAC value if the mid upper arm position is determined visually as opposed to being measured in the 'classical' fashion

NCT ID: NCT01529125 Completed - HIV Clinical Trials

Safety and Metabolic Study of Highly Active Antiretroviral Therapy (HAART) in Malnourished Children With HIV

ARMAM
Start date: July 2011
Phase: N/A
Study type: Observational

It is unclear whether children with HIV and severe acute malnutrition can be started on highly active antiretroviral therapy (HAART) safely while they are still malnourished and the manner in which this therapy should start. This study will examine the safety, efficacy, and metabolism of children started on HAART while still severely malnourished.

NCT ID: NCT01041456 Completed - Clinical trials for Metabolic Bone Disease

Laparoscopic Revision From Biliopancreatic Diversion to Gastric Bypass

BPD-to-RYGB
Start date: March 2009
Phase: N/A
Study type: Observational

The aim of this study is to describe the clinical presentation, indications, and operative treatment as well as assess the morbidity, mortality, and overall performance of revisional GBP after either failed and/or complicated Biliopancreatic Diversion "BPD" for weight loss. With such information, we hope to determine what features might assist us in advancing our knowledge about mechanisms of failure after primary bariatric surgery, mechanism of action of revisional GBP, and performance of revisional GBP through traditional outcome measurements as well as identifying predictors of good or poor outcome after revisional GBP in this specific subpopulation.