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Kidney Stone clinical trials

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NCT ID: NCT05995652 Completed - Kidney Stone Clinical Trials

Can Shear Wave Elastography Predict the Success of ESWL: a Prospective Study

Start date: August 30, 2023
Phase:
Study type: Observational

Can Shear Wave Elastography predict the success of Shock-Wave Lithotripsy used in renal stones treatment ? A prospective study

NCT ID: NCT05852483 Completed - Kidney Stone Clinical Trials

Predictors of Readmission in Patients Undergoing PNL

Start date: April 1, 2022
Phase:
Study type: Observational

To identify predictors of patients postoperative readmission after PNL

NCT ID: NCT05714423 Completed - Kidney Stone Clinical Trials

Outcomes in Lower Pole Kidney Stone Management Using Mini-PCNL Compared With Retrograde Intra Renal Surgery

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Due to the anatomic characteristics of the lower calyx, lower pole stones are difficult to be eliminated through the ureter, even if the stones had been fragmented. Retrograde intrarenal surgery (RIRS) can be used to deal with lower pole stones of 1.0-2.0 cm, while percutaneous nephrolithotripsy (PCNL) is mainly used to deal with lower pole stones with larger diameter or when RIRS failed to resolve the stone. This study was conducted to compare mini PCNL and retrograde intrarenal surgery (RIRS) for the management of lower pole kidney stones in terms of efficacy.

NCT ID: NCT05431049 Completed - Anesthesia Clinical Trials

Anesthesia Type on Percutaneous Nephrolithotomy in Aging Male

Start date: May 7, 2021
Phase:
Study type: Observational

The aim of this study is to compare the anesthesia methods in percutaneous nephrolithotomy in terms of safety and effectiveness in elderly men.

NCT ID: NCT05153629 Completed - Kidney Stone Clinical Trials

Noninvasive Electrical Stimulator as a Pain Control Treatment Post-ureteroscopy

Start date: January 10, 2021
Phase: N/A
Study type: Interventional

The investigators will assess the use of Transcutaneous Neurostimulation (TENS), a pharmacological alternative, for treatment of ureteral stent pain post-ureteroscopy. The primary aim for the investigators is to determine if use of a TENS unit will reduce post-operative pain and nausea associated with the ureteral stent. Secondary aim will be to assess if it can help minimize narcotic use.

NCT ID: NCT04911660 Completed - Kidney Stone Clinical Trials

Impact of the SGLT2 Inhibitor Empagliflozin on Urinary Supersaturations in Kidney Stone Formers

SWEETSTONE
Start date: August 25, 2021
Phase: Phase 2
Study type: Interventional

The aim of this study is to test the effect of a new drug on the composition of the urine in kidney stone patients. This new drug (Jardiance®, substance: empagliflozin) is currently approved in Switzerland for the treatment of patients with diabetes. Data from previous studies with and without diabetes suggest that it may have a beneficial effect on the composition of the urine and thereby reduce the risk of developing kidney stones.

NCT ID: NCT04804436 Completed - Kidney Stone Clinical Trials

Protein Kinase 2 (HIPK2) Polymorphisms on rs2058265, rs6464214, and rs7456421

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

In the present study investigators aimed to investigate whether homeodomain interacting protein kinase 2 (HIPK2) polymorphism is associated with renal stone formation in Turkish population or not. One hundred and twenty nine participants with calcium nephrolithiasis and 67 sex and age-matched healthy controls were enrolled in this study. For analysis of HIPK2 polymorphism, the real-time PCR amplification was performed in a final volume of 20μL reaction mixture, including 10 ng of genomic DNA, 5 µL of TaqMan® Universal PCR Master Mix, and 0.5 µL of 40X TaqMan® assay. The Rotor-Gene Q Series Software Version Q 2.3.1 (Rotor-Gene Q Series, Ziagen) was used for allelic discrimination. Chi square test was utilized to compare the differences of the genotype and allele frequencies between patients and controls.

NCT ID: NCT04557722 Completed - Kidney Stone Clinical Trials

The Newly Reported (0-90°) Versus (0-30°) Biplanar Fluoroscopic Puncture Technique in PCNL

Start date: May 24, 2021
Phase: N/A
Study type: Interventional

To analyze and compare the puncture success rate, puncture fluoroscopy time and intraoperative puncture complications of two different puncture techniques; fluoroscopic bi-planar (0-30º) versus newly reported bi-planar (0-90º) technique in PCNL.

NCT ID: NCT04556201 Completed - Kidney Stone Clinical Trials

The Performance of the SOLTIVE Laser System for Laser Lithotripsy in Kidney or Ureteral Stones

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to collect real-world evidence on the performance of the SOLTIVE™ Premium SuperPulsed Laser System for laser lithotripsy in ureteroscopy, percutaneous nephrolithotomy (PCNL) and mini PCNL for kidney and ureteral stones.

NCT ID: NCT04435132 Completed - Kidney Stone Clinical Trials

Robotic-assisted Percutaneous Access

Start date: August 7, 2018
Phase: N/A
Study type: Interventional

This is a first-in-man (FIM) study to show feasibility and safety profile of the newly developed robotic device for percutaneous access in PCNL surgery. Patients with renal stone disease who had standard indications for prone PCNL were included in the study. PCNL was conducted with percutaneous puncture with the aid of robotic device with the use of intra-operative fluoroscopy. 5 patients were recruited in this pilot study over a period of 3 months. Punctures were performed by the board-qualified urologist.