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How Vitamin D Analogues Affect Endothelial Cells in Patients on Dialysis

Kidney Failure, Chronic Clinical Trial

Official title:
Effect of Doxercalciferol on Endothelial Cell Function in End Stage Renal Disease

Clinical Trial Summary

Patients with chronic kidney disease and end stage renal disease have greater cardiovascular risk than the general population. Vitamin D analogues have been shown in observational studies to have mortality benefit for these patients. This study is designed to investigate doxercalciferol's effect on the vasculature (i.e. endothelial cell function) as a possible mechanism to explain the mortality benefit.

Clinical Trial Description

n/a

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00528788
Study type Interventional
Source Duke University
Contact
Status Completed
Phase Phase 4
Start date September 2007
Completion date August 2012
View Details
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