Clinical Trials Logo
  1. Home
  2. Kidney Calculi
  3. NCT03018899

Paravertebral Block Versus Epidural Anesthesia for Percutaneous Nephrolithotomy — PVB  

Kidney Calculi Clinical Trial

Official title:
Comparison of Paravertebral Block Versus Epidural Anesthesia for Surgical Anesthesia of Percutaneous Nephrolithotomy

Clinical Trial Summary

This prospective, randomized study is aimed to assess the efficacy and safety of paravertebral block compared to epidural anesthesia for percutaneous nephrolithotomy. The investigators suppose that paravertebral block is not inferior in controlling the perioperative pain for percutaneous nephrolithotomy compared to epidural block.

Clinical Trial Description

Background: Percutaneous nephrolithotomy (PCNL) is generally performed under general or neuraxial anesthesia. The investigators have reported three patients who were at high risk of both general anesthesia and neuraxial anesthesia received percutaneous nephrolithotomy with ultrasound guided paravertebral block. Then，The investigators performed ultrasound guided paravertebral block for 45 patients who received percutaneous nephrolithotomy successfully. The investigators' impression is that paravertebral block is as effective as epidural anesthesia for surgical anesthesia of percutaneous nephrolithotomy.

Objectives:To assess the efficacy and safety of paravertebral block compared to epidural anesthesia for surgical anesthesia of percutaneous nephrolithotomy.

Methods: Fifty adult patients undergoing elective percutaneous nephrolithotomy will be randomized to receive ultrasound guided paravertebral block or epidural anesthesia. The primary outcome will be the pain score 12h postoperation. The secondary outcomes will include: time spent to perform block, dose of intraoperative opioids, rate of hypotension need for vasoconstrictors, muscle Power Grading of the lower legs at the end of the operation, anus exhaust time, opioid consumption postoperation, postoperative PONV score and the frequency of vomiting , hospitalization duration and patient satisfaction.

Clinical Implications: Ultrasound guided paravertebral block could be an equally effective and safe alternative to epidural block for surgical anesthesia of percutaneous nephrolithotomy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03018899
Study type Interventional
Source Huazhong University of Science and Technology
Contact
Status Completed
Phase N/A
Start date September 2016
Completion date July 2017
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05100017 - Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure N/A
Recruiting NCT04559321 - Holmium Vs Trilogy Kidney Stones GUY's 1-2 Phase 3
Completed NCT04332861 - Evaluation of Infection in Obstructing Urolithiasis
Recruiting NCT05578807 - Total Tubeless Percutaneous Nephrolithotomy Without a Ureteral Catheter N/A
Recruiting NCT02489656 - Quality of Life in Patients With Double Loop Ureteral Stent (JJ Silicone Hydrogel Study) Phase 4
Completed NCT00177086 - Alfuzosin Hydrochloride to Promote Passage of Distal Ureteral Calculi Phase 3
Completed NCT03957109 - Influence of Anesthesia Methods on Surgical Outcomes and Renal Function N/A
Active, not recruiting NCT05082142 - Tranexamic Acid to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP) Phase 4
Completed NCT05911945 - Failed Insertion of Ureteral Access Sheath During Flexible Ureterorenoscopy N/A
Recruiting NCT03599297 - Bilateral Synchronous Simultaneous Stone Surgery N/A
Recruiting NCT05701098 - SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD) N/A
Completed NCT03888144 - Study of Ketorolac Versus Opioid for Pain After Endoscopy Phase 4
Withdrawn NCT04545528 - The Impact of Nutritional Service in the Stone Clinic on the Patient Urine Collection Results
Recruiting NCT05598671 - Percutaneous Nephrolithotomy Without a Ureteral Catheter N/A
Completed NCT05511545 - The Effect of Education Given to Patients on Pre- and Post-operative Anxiety and Preparation for Discharge N/A
Not yet recruiting NCT04606758 - Fluoroscopic Guided vs US-guided Percutaneous Nephrolithotripsy for the Treatment of Stone Disease N/A
Recruiting NCT03855787 - Ureteral Stent Placement After Ureteroscopy for Renal Stones: A Randomized Controlled Trial N/A
Completed NCT04069338 - Comparison of Lithotripsy Urolithiasis Machines N/A
Completed NCT01329042 - Efficacy of Potassium Sodium Hydrogen Citrate Therapy on Renal Stone Recurrence and/or Residual Fragments After Shockwave Lithotripsy and Percutaneous Nephrolithotomy in Calcium Oxalate Urolithiasis Phase 4
Recruiting NCT06331546 - Gut Oxalate Absorption in Calcium Oxalate Stone Disease N/A