Clinical Trials Logo

Ketosis clinical trials

View clinical trials related to Ketosis.

Filter by:
  • Completed  
  • Page 1 ·  Next »

NCT ID: NCT06327737 Completed - Metabolic Acidosis Clinical Trials

Diabetic Ketoacidosis Diagnosis and Management

Start date: December 15, 2020
Phase:
Study type: Observational [Patient Registry]

This is the first and only study conducted on the use of capnography in children diagnosed with DKA to evaluate the initial clinical grading of DKA, monitor clinical improvement, and predict complications such as brain edema.

NCT ID: NCT06251895 Completed - Clinical trials for Diabetic Ketoacidosis

Association of Systemic Immune-inflammation Index and Severity of Diabetic Ketoacidosis in Type 1 Diabetes Mellitus

Start date: August 1, 2021
Phase:
Study type: Observational

Diabetic ketoacidosis (DKA) is the most serious metabolic complication of type 1 diabetes mellitus (T1DM). Insulin deficiency and inflammation play a role in the pathogenesis of DKA. The investigators aim to assess the systemic immune-inflammation index (SII) as a marker of severity among T1DM patients with DKA and without infection.

NCT ID: NCT06060093 Completed - Sleep Clinical Trials

Effect of Ketone Ester Supplementation on Sleep and Recovery in Hypoxia

Start date: February 20, 2023
Phase: N/A
Study type: Interventional

This study specifically aims to elucidate the effects of IEK on sleep and recuperation in hypoxia, after training in normoxia. These conditions are in line with the widely applied live-high train-low strategy. Moreover, blood and tissue oxygenation status, as well as cerebral blood flow and cognitive function will be assessed.

NCT ID: NCT05980858 Completed - Ketosis Clinical Trials

Effects of Exogenous Ketosis on Renal Function, Renal Perfusion, and Sodium Excretory Capacity in Healthy Subjects

KETO
Start date: August 10, 2023
Phase: N/A
Study type: Interventional

This is a randomized, placebo-controlled, double-blinded crossover design. Fifteen healthy subjects will be randomized to receive either ketone bodies (KE4) or placebo delivered by KetoneAid. After a period of 5-days treatment, effect variables will be measured (experiment day 1). After a washout period of 14 days, the subjects are crossed over to a similar treatment period with the other treatment. The study is terminated by measuring effect variables after the second treatment period (experiment day 2).

NCT ID: NCT05939011 Completed - Ketosis Clinical Trials

Ketogenic Diet Health and Longevity

KDHL
Start date: April 8, 2022
Phase: N/A
Study type: Interventional

The goal of this pilot intervention is to learn about how a well-formulated ketogenic diet (WFKD) impacts various health factors in generally healthy adults. The main questions it aims to answer are: - Establish whether an 8-week isocaloric, WFKD improves body composition and metabolic biomarkers in adults without chronic disease. - Examine changes in transcriptomic sequencing pathways pre- and post-WFKD intervention. - Explore gut microbial changes in adults without chronic disease that consume a WFKD. Participants will follow a well-formulated ketogenic diet for 8-weeks. Study procedures include: - Weekly body weight tracking - Daily urinary ketone assessment - Pre/post stool samples for gut microbiota analyses - Pre/post DXA scans - Diet quality tracking through 3-day food records

NCT ID: NCT05808972 Completed - Acetonuria Clinical Trials

0.9% Saline Versus Balanced Solutions in Severe Diabetic Ketoacidosis

Start date: November 1, 2022
Phase: Phase 4
Study type: Interventional

Severe diabetic ketoacidosis (DKA) is a potentially serious complication of diabetes mellitus. The treatment regimen is based on insulin and rehydration. The choice of rehydration solution is a question that remains open. We sought to compare the effect of sodium chloride 0.9% (SC) versus ringer lactate (RL) in the resolution of severe DKA as well as on the variation of electrolytes.

NCT ID: NCT05699707 Completed - Ketosis Clinical Trials

Metabolomic Signature of Exogenous Ketosis

KM
Start date: February 1, 2023
Phase: N/A
Study type: Interventional

Ketone bodies are a fuel source and signaling molecule that are produced by your body during prolonged fasting or if you consistently eat at low-carbohydrate diet. Blood ketones can be used as a source of energy during fasting and are used by your brain as an alternative source of fuel to glucose. Previous studies have found that ketones, when consumed in form of a supplement drink, can increase blood ketone levels and lower blood glucose, the amount of sugar in your blood. This is of potential interest for individuals with high blood sugar, such as people living with type 2 diabetes. However, how ketone supplements impact metabolism is not fully understood but using high throughput analysis techniques that can characterize hundreds to thousands of metabolites in the blood (known as "metabolomics") may allow researchers to discover novel compounds within the body that are altered by ketone supplements. This will improve our understanding of how ketones impact metabolism and guide future research.

NCT ID: NCT05665855 Completed - Exercise Clinical Trials

The Effects of Acute Ketone Monoester Supplementation on Exercise Efficiency and the Influence of Dose and Intensity

Start date: December 27, 2022
Phase: N/A
Study type: Interventional

Diet can alter blood ketone levels and this in turn may affect exercise capacity. This study will determine if the acute ingestion of a ketone supplement alters cycling exercise efficiency. Participants will perform three trials in a randomized order. Each trial will involve an incremental exercise protocol on a stationary cycle ergometer to volitional fatigue. Participants will ingest either a high or low dose of a ketone supplement or a taste-matched placebo drink prior to exercise. Blood samples will be obtained to assess selected metabolic responses. This study will provide information regarding the effect of ketone supplementation on exercise efficiency.

NCT ID: NCT05597605 Completed - Clinical trials for Diabetes Mellitus, Type 2

The SHINE Study: Safety of Implant and Preliminary Performance of the SHINE SYSTEM in Diabetic Subjects

Start date: September 21, 2022
Phase: N/A
Study type: Interventional

The objectives of SHINE study are to confirm the safety aspects of the SHINE SYSTEM. Moreover, the goal of this clinical investigation is the initial evaluation of sensor's performance by assessing sensor's ability to qualitatively detect the appropriate analytes in subjects with diabetes of 18 years and older.

NCT ID: NCT05588427 Completed - Hypoxia Clinical Trials

Effect of Ketone Ester Supplementation on Hypoxic Tolerance

Start date: November 15, 2022
Phase: N/A
Study type: Interventional

This WP specifically aims to elucidate the effects of IEK on hypoxic tolerance and the development and severity of AMS symptoms, blood and tissue oxygenation status, as well as sleep quality during an episode of acute exposure to severe hypoxia.