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Joint Diseases clinical trials

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NCT ID: NCT04183985 Not yet recruiting - Knee Arthropathy Clinical Trials

Comparison of Radiological, Clinical, Functional Outcomes Between Anatomically Aligned Total Knee Arthroplasty and Conventional Total Knee Arthroplasty

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Total knee arthroplasty(TKA) is a successful orthopedic surgery with excellent clinical outcome and survival. However, there are concerns about patient satisfaction in previous reports, and dissatisfaction rate of 15-30% is reported in clinical outcomes(PROMs) of some studies. Therefore, for improving the patient's outcome and satisfaction after total knee arthroplasty, it is necessary to change the design of the conventional total knee arthroplsaty implant. The knee is a joint structure with several dynamic functions, and not only the skeletal structure but also the soft tissue balance plays an important role in the function of the knee joint. New implants are being developed to overcome the limitations of conventional TKA implant, including the Journey II Bi-cruciate substituting total knee system (JII-BCS; Smith & Nephew). JII-BCS implant has normal articular geometry, more anatomical femoral shape, lateral tibial convex geometry, and asymmetrical tibial plateau, anterior and posterior cams, which has been shown in experimental studies to produce nearly normal knee movement by reproducing the actual normal anatomical alignment in vivo. The clinical results of the kinematic effects of this anatomcally aligned change are insufficient, and there is also a lack of comparative studies with conventional total knee arthroplasty implant. The purpose of this study is to compare outcomes between anatomically aligned TKA(JII-BCS) and conventional TKA(Legion total knee system, Smith & Nephew). This study is a randomized controlled study in patients undergoing same-day bilateral total knee arthroplasty. A patient undergoing same-day bilateral total knee arthroplasty will use a random number to determine the instruments(JII-BCS or Legion), and both knee joints will be operated with the same instruments. Radiologic parameter, patients preference and clinical results was investigated in patients who received TKA during minimum 2 year follow up.

NCT ID: NCT04149366 Not yet recruiting - Clinical trials for Temporomandibular Joint Disorders After Using Essix Retainer

Clinical and Radiographic Evaluation of Different Thickness of Vacuum Formed Retainer (Essix Retainer) During Retention Phase After Orthodontic Treatment

Start date: October 29, 2019
Phase:
Study type: Observational

vacuum formed retainer act as bite raiser that increase vertical dimension which may affect Tempromandibular joint and aim of this study is to perform clinical and radiographic evaluation of different thickness of vacuum formed retainer (Essix retainer) during retention phase after orthodontic treatment

NCT ID: NCT04102046 Not yet recruiting - Clinical trials for Hemophilia Arthropathy

Quality of Life in Hemophilia by Clinical Scoring System (FISH)Score

Start date: June 28, 2020
Phase:
Study type: Observational

To asses quality of life in patients with hemophilia clinically.- -To avoid or minimize structural damage to goints and muscles by making patients aware of importance of rehabilitation

NCT ID: NCT04093804 Not yet recruiting - Clinical trials for Rotator Cuff Tear Arthropathy

Impact of Glenosphere Size on Range of Motion in Female Patients Undergoing Reverse Shoulder Arthroplasty

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to perform a prospective randomized trial among female patients undergoing reverse shoulder arthroplasty (RSA) to determine if a larger glenosphere allows greater range of motion without an impact on complications.

NCT ID: NCT04084912 Not yet recruiting - Arthropathy of Knee Clinical Trials

Effect of Preoperative Steroid in Total Knee Arthroplasty

Start date: January 1, 2020
Phase: Phase 3
Study type: Interventional

Detect the effect of preoperative steroid injection in total knee arthroplasty on post operative: 1. pain 2. oedema 3. nausea and vomiting 4. quadriceps power 5. knee flexion 6. wound complications

NCT ID: NCT04050111 Not yet recruiting - Knee Osteoarthritis Clinical Trials

The Evaluation of Safety and Effectiveness of Intraarticular Administration of Autologous Stromal-Vascular Fraction of Adipose Tissue Cells for Treatment of Knee Joint Arthrosis

Start date: August 21, 2019
Phase: Phase 2
Study type: Interventional

Stromal vascular fraction of cells (SVF) will be extracted from lipoaspirate by enzymatic digestion. SVF will be administered in a single dose intraarticularly. All patients will receive cell therapy.This is a single arm study with no control.

NCT ID: NCT04039308 Not yet recruiting - Deformity, Foot Clinical Trials

Assessment of Surgical Correction of Deformity in Diabetic Charcot Arthropathy of the Foot and Ankle

Start date: October 1, 2019
Phase:
Study type: Observational

The surgical techniques described in the literature for surgical management of diabetic charcot arthropathy of the foot and ankle include simple exostectomy, open reduction and internal fixation of neuropathic fractures, external fixation, arthrodesis, Achilles tendon lengthening. Patients are followed up at 1 year postoperative by an x-ray of the foot and ankle anteroposterior , lateral and oblique views to assess rate of union ,the correction of deformity by measuring the foot angles . The functional outcome is assessed by the AOFAS scoring system and the diabetic foot ulcer scaoeuulcer scale(18).

NCT ID: NCT04001699 Not yet recruiting - Multimorbidity Clinical Trials

Interprofessional Preoperative Geriatric Assessment for Older Arthroplasty Patients With Multimorbidity

IPPGA-RCT
Start date: August 19, 2019
Phase: N/A
Study type: Interventional

The objective of this randomized control trial is to investigate effects and cost effectiveness of interprofessional preoperative assessment among older knee or hip arthroplasty patients. The main hypothesis is that preoperative assessment and optimization have a positive impact on the patents' quality of life and expenditure of social and health care services.

NCT ID: NCT03765723 Not yet recruiting - Anesthesia Clinical Trials

Prediction Model of Acute Postoperative Pain in Bilateral Total Knee Replacement Arthroplasty Patient

Start date: January 1, 2019
Phase:
Study type: Observational

This study aims to predict risk factors of acute postoperative pain of the patients undergoing Total Knee Replacement Arthroplasty(TKRA).

NCT ID: NCT03726788 Not yet recruiting - Clinical trials for Magnetic Resonance Imaging

Intra Articular Injection of Botulinum Toxin Versus Corticoids in Gonarthrosis

TOXART
Start date: September 2019
Phase: Phase 2
Study type: Interventional

We believe we can demonstrate a link between the analgesic action of intra-articular injection of botulinum toxin and synovial inflammation by Dynamic Contrast Enhancement (DCE) perfusion Magnetic Resonance Imaging (MRI).