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IVM clinical trials

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NCT ID: NCT06369415 Recruiting - Infertility Clinical Trials

Health of Babies Born From IVF Versus IVM at 5 Years Old

FM-BABIES-5Y
Start date: April 16, 2024
Phase:
Study type: Observational

The investigators conduct a long-term follow-up at five years on offspring born from our randomized controlled trial (RCT) to investigate whether or not there is any difference in developmental outcomes in children born after capacitation IVM (CAPA IVM) compared with conventional IVF in order to give strong evidence about the safety of IVM in women with high antral follicle count.

NCT ID: NCT04774432 Recruiting - IVF Clinical Trials

Effect of GM-CSF on CAPA-IVM System Success Rates in PCOS

Start date: March 10, 2021
Phase: N/A
Study type: Interventional

In-vitro maturation (IVM) of human oocytes obtained from minimally stimulated or unstimulated ovaries offers a more "patient friendly" treatment option than the conventional Assisted Reproductive Technology (ART) treatment with controlled ovarian hyperstimulation (COH). However, maturation rate and the total blastocyst yield in oocytes undergoing in vitro maturation are still limited. This pilot study aims to evaluate the addition of an important growth factor known as Granulocyte macrophage colony stimulating factor (GM-CSF). The investigators hypothesize that the addition of GM-CSF to human IVM culture media will increase pregnancy rates to comparable levels to that of IVF, making it a viable clinical option for couples undergoing assisted reproductive treatment.