BPA Levels Relationship With IVF/ICSI Outcomes in Patients With Male Factor

IVF Clinical Trial

Official title:

Impact of Blood and Ejaculate Bisphenol A Concentrations on ICSI Cycles Outcome in Patients With Male Factor

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05224284
• Other study ID #: 2019/21
• Status: Completed
• Phase: N/A
• Start date: May 1, 2019
• Est. completion date: October 30, 2019

Study information

• Verified date: January 2022
• Source: Sanliurfa Mehmet Akif Inan Education and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Association between blood and semen BPA levels and ICSI outcomes in patients with male factor

Recruitment information / eligibility

• Status: Completed
• Enrollment: 75
• Est. completion date: October 30, 2019
• Est. primary completion date: October 30, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 23 Years to 45 Years

Eligibility

Inclusion Criteria:

• female patients aged 23-40 years who underwent IVF due to male factor

• men with semen sample obtained from ejaculate

• male patients provided blood, and ejaculate samples on the oocyte retrieval day

• patients who did not smoke or use alcohol

• patients did not work in the plastic industry

Exclusion Criteria:

• men with a diagnosis of azoospermia

• patients who underwent IVF due to low ovarian reserve or unexplained infertility indications

• patients diagnosed with endometriosis

• patients with freeze-all cycles

• women with metabolic disease (such as hypertension or diabetes mellitus)

• patients (male or females) with a known genetic problem (male or female)

Related Conditions & MeSH terms

• Infertility
• Infertility, Male
• IVF

Intervention

Other:
• BPA levels
BPA (Bisfenol A) in blood and ejaculate samples

Locations

Country	Name	City	State
Turkey	Nefise Nazli YENIGUL	Bursa

Sponsors (1)

Lead Sponsor	Collaborator
Sanliurfa Mehmet Akif Inan Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Exposure to BPA	Concentrations of Bisphenol A (BPA) will be quantified in the blood plasma, and ejaculate (individual and pooled samples) by use of ELISA test in women with male factor	6 month