Ischemia Re-perfusion Injury Clinical Trial
Official title:
Impact of Pre-treatment of Living-donor Liver Transplant Recipients With Omega 3 Enriched Lipid Emulsions on Graft and Patient Outcome. A Prospective, Randomized, Multi-central Trial.
The study Aims to investigate the possible beneficial impact of peri-operative or post-operative administration of Omega 3 enriched lipid emulsions on recipients for living donor liver transplantation.
Patients will be divided intro three groups, A control group will receive equivalent volume
of glucose 10% solution both 3 days before and 5 days after the operation .
A peri-operative groups, in which patients will receive omega 3 enriched lipid emulsion
(SMOFLipid) for 2 days pre-transplantation and 5 days post-transplantation A Post-operative
group, in which patients will receive glucose 10% 3 days before the operation and omega 3
enriched lipid emulsion (SMOFLipid) for 5 days post-transplantation The primary outcome
objective will be the incidence of Ischemia re-perfusion injury, secondary outcomes includes
post-operative complications, graft and patient's outcomes and graft regeneration
;