Effects of Low FODMAP Diet on Leaky Gut

Status Active, not recruiting

Clinical Trial Summary

The pathophysiology of Irritable bowel syndrome (IBS) is multifactorial involving complex interplay of altered intestinal permeability, mucosal immune activation, visceral hypersensitivity and gut dysbiosis. Although the exact triggers for these pathological changes in IBS are not clear but diet might play an important role. In fact, several studies have reported improvement in gastrointestinal symptoms on a diet low in FODMAPs (LFD) in patients with IBS, specifically in diarrhea predominant IBS (IBS-D). However, the mechanism of action of LFD is not well understood.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04526808
Study type	Interventional
Source	Beth Israel Deaconess Medical Center
Contact
Status	Active, not recruiting
Phase	N/A
Start date	May 20, 2019
Completion date	June 1, 2025

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