Irritable Bowel Syndrome Clinical Trial
Irritable bowel syndrome is characterized by abdominal discomfort and bowel habit change. It
is increasing worldwide. But the pathophysiology of the irritable bowel syndrome is not
proven. So, the treatment's target is the relief of the symptoms.
Small intestinal bacterial overgrowth considered as the cause of the irritable bowel
syndrome. Because, it is related to the postprandial abdominal discomfort and the abdominal
discomfort could be relieved after taking antibiotics. There are several diagnostic methods
for small intestinal bacterial overgrowth. hydrogen breath test is non-invasive method for
diagnosis of the small intestinal bacterial overgrowth. But, there is no standardized cut-off
value for the hydrogen breath test. So, we want to compare the hydrogen breath test between
the irritable bowel syndrome patients and normal people. And then, we want to analyze the
efficacy of hydrogen breath test for the diagnosis of irritable bowel syndrome.
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