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NCT00100425 Clinical Trial

Characterization of Pain Processing Mechanisms in Irritable Bowel Syndrome

Irritable Bowel Syndrome Clinical Trial

Official title:
Central Nervous System Modulation of Visceral Pain in Persian Gulf War Syndrome

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00100425
Other study ID # CADE-ARCD2
Secondary ID
Status Completed
Phase N/A
First received December 30, 2004
Last updated January 20, 2009
Start date September 2000

Study information
Verified date December 2004
Source VA Office of Research and Development
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Interventional

Clinical Trial Summary

The purpose of this study is to provide new information and to determine which kinds of brief, tolerable, experimental pain are affected by the drugs being studied in patients with irritable bowel syndrome, a disease that causes chronic abdominal pain. The effects of dextromethorphan, naloxone, and fentanyl on experimental pain stimuli will be tested in these studies to better understand what causes irritable bowel syndrome.

Recruitment information / eligibility
Status Completed
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 72 Years
Eligibility - Patients with irritable bowel syndrome and healthy pain-free individuals (as controls) will be studied.

- No medical condition that would contraindicate use of dextromethorphan, fentanyl or naloxone.

Study Design

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Intervention

Procedure:
• Viceral Perception Testing

Locations
Country Name City State
United States Malcolm Randall VA Medical Center Gainesville Florida

Sponsors (1)
Lead Sponsor Collaborator
VA Office of Research and Development

Country where clinical trial is conducted

United States, 

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