Clinical Trials Logo
  1. Home
  2. Irreversible Pulpitis
  3. NCT05306431

Comparison of Antimicrobial Action of Sodium Hypochlorite and Polyhexamethylene Biguanide as Root Canal Irrigants

Irreversible Pulpitis Clinical Trial

Official title:
Comparison of Antimicrobial Action of Sodium Hypochlorite and Polyhexamethylene Biguanide as Root Canal Irrigants in Patients Reporting With Non-vital Necrotic Pulp and Apical Periodontitis

Clinical Trial Summary

The aim of this randomized clinical trial is to compare the antibacterial effects of sodium hypochlorite (NaOCl) and Polyhexamethylene biguanide during root canal treatment .

Clinical Trial Description

This study will compare the antibacterial effectiveness of sodium hypochlorite and PHMB, to find out whether PHMB can be used as a substitute to NaOCL. Polyhexamethylene biguanide (PHMB), is a disinfectant solution having a broad spectrum of antimicrobial activity and is investigated as an endodontic irrigant. It is non-corrosive, non-toxic and acts by disrupting cell membrane integrity. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05306431
Study type Interventional
Source Altamash Institute of Dental Medicine
Contact
Status Completed
Phase Phase 2
Start date June 1, 2022
Completion date November 30, 2022
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT04585438 - Evaluation of Trans-mucosal Bio-adhesive Discs of Diclofenac Potassium on the Anesthetic Success and Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial Phase 4
Completed NCT02923687 - Premedication Efficacy of Ketorolac Infiltration on Post Endodontic Pain Phase 2
Completed NCT02601911 - Effect of Premedication on Success of Inferior Alveolar Nerve Block Injection Phase 2
Completed NCT02614118 - Premedication Efficacy of Oral Ketorolac and Ketorolac/ Acetaminophen on Post Treatment Pain Phase 2
Completed NCT01496846 - Efficacy Study of Articaine Versus Lidocaine as Supplemental Infiltration in Inflamed Molars Phase 4
Withdrawn NCT04040127 - Residual Dental Pulp Tissue and Cord Blood Stem Cells Phase 2
Completed NCT06176378 - A Clinical and Radiographic Evaluation of Low-Level Diode Laser Full Pulpotomy in Vital Permanent Teeth N/A
Recruiting NCT04243733 - MTA vs CEM Pulpotomy in Young Permanent Molars N/A
Recruiting NCT06245161 - Efficacy of Computer Controlled Intraosseous Anesthesia in Pediatric Dental Patients N/A
Not yet recruiting NCT04573374 - Comparing the Outcome of Pulpotomy Using Biodentine and Portland Cement in Mature Cases With Irreversible Pulpitis: Randomized Clinical Trial N/A
Completed NCT05778227 - Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion. N/A
Completed NCT04654845 - Patient Perception Between Two Emergency Treatments of Symptomatic Irreversible Pulpitis. N/A
Recruiting NCT06142799 - Influence of Moment of Restoration in Pain After a Root Canal Treatment N/A
Active, not recruiting NCT06240130 - Outcome Following Use of NaOCl and Chlorhexidine as Wound Lavage Agents N/A
Not yet recruiting NCT05349929 - Analgesic Effect of Anahil and Ibuprofen on Pain After Root Canal Therapy in Patients With Pulpitis of the Molars in Qazvin(a City in Iran) Phase 2
Recruiting NCT06149845 - Pulpotomy in Vital Primary Molars Diagnosed With Symptomatic Irreversible Pulpitis N/A
Completed NCT01561183 - Vital Pulp Therapy (VPT) Using Calcium Enriched Mixture (CEM) to Treat Irreversible Pulpitis N/A
Recruiting NCT06231290 - The Influence of Magnification and Clinical Experience on the Outcome of Pulpotomy in Mature Adult Teeth N/A
Not yet recruiting NCT05277246 - Effect of Using Different Concentrations of NaOCI on IL-8 Level N/A
Completed NCT06081335 - Can Instrumentation Kinematics Affect Post Operative Pain and Substance P Levels? A Randomized Controlled Trial N/A