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Iron Deficiency Anemia clinical trials

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NCT ID: NCT04130828 Completed - Clinical trials for Iron Deficiency Anemia

Thrice-weekly Versus Thrice-daily Oral Ferrous Fumarate Treatment in Adult Patients With Iron Deficiency Anemia

Start date: January 21, 2020
Phase: Phase 3
Study type: Interventional

Iron deficiency anemia is a global health problem and the most common cause of anemia worldwide. Patients with iron deficiency and Iron deficiency anemia can present with a multitude of symptoms including fatigue, dyspnea on exertion, dysphagia, pallor, palpitations, headaches, tinnitus, taste disturbance and pica. Oral iron supplementation is associated with increasing hemoglobin in multiple studies in women, pregnant women and elderly patients. However, the optimal dose and frequency of oral iron supplementation for treatment remains unclear. The current proposed study attempts to address this gap in the literature.

NCT ID: NCT04079322 Completed - Clinical trials for Iron Deficiency Anemia

Iron Absorption and Exercise

Start date: August 22, 2019
Phase: N/A
Study type: Interventional

Iron is a nutritionally essential mineral required for optimal physical and cognitive performance. Endurance exercise often leads to declines in iron status; however, the reason for the decline is not known. The primary objective of the proposed study is to determine the effects of an acute bout of strenuous endurance exercise on iron absorption and status and markers of inflammation in human volunteers. The investigators hypothesize that an acute bout of strenuous endurance exercise, compared to rest, will reduce iron absorption, resulting in diminished iron status, and that reduced iron absorption will be negatively associated with markers of inflammation. A secondary objective is to monitor iron status throughout a season of competition.

NCT ID: NCT04018300 Completed - Clinical trials for Iron Deficiency Anemia

Iron Supplementation and Side Effects

Start date: January 8, 2018
Phase: N/A
Study type: Interventional

The objective of this study is to examine patient-reported gastrointestinal side effects, as well as iron status indicators, inflammatory markers and oxidative stress following administration of ferrous sulfate and iron-enriched Aspergillus oryzae supplementation.

NCT ID: NCT03940430 Completed - Clinical trials for Iron Deficiency Anemia

Lactoferrin Versus Ferrous Sulfate in Management of Iron Deficiency Anemia Among Female Medical Ain Shams Students

Start date: September 10, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This study aims to compare the efficacy of lactoferrin versus iron supplementation versus two combined supplementation on iron deficiency anemia in female medical Ain Shams students by using iron profile.

NCT ID: NCT03840031 Completed - Clinical trials for Iron Deficiency Anemia

Iron Bioavailability From Biofortified Orange-fleshed Sweet Potato

SASHA-II
Start date: March 25, 2019
Phase: N/A
Study type: Interventional

To combat iron deficiency in Low and Middle-Income Countries, sustainable food-based solutions have to be implemented to serve populations, not only individuals. One solution is the introduction of iron biofortified staple crops on market level. Before market level introduction, the bioavailability of iron in the new biofortified Orange Fleshed Sweet Potato (OFSP) breed needs to be assessed. In this study the investigator compares the fractional and total iron absorption after extrinsic stable isotope labelling of the new biofortified high iron OFSP variety and a normal market level OFSP variety. The study is conducted in Malawian women of reproductive age with marginal iron status.

NCT ID: NCT03835364 Completed - Anemia Clinical Trials

Aptus at Home: Co-design of a Home-based Monitoring System for Anaemia

Start date: April 13, 2018
Phase:
Study type: Observational

Co-design of a home-based anaemia monitoring system with participants who have previous diagnosis of anaemia.

NCT ID: NCT03819530 Completed - Clinical trials for Iron Deficiency Anemia

Child of Urban Poverty Iron Project (CUPIP) - A Pilot Study

CUPIP
Start date: September 16, 2019
Phase: N/A
Study type: Interventional

The first 1,000 days of life are critical periods for brain development. Proper nutrition lays the foundation for optimal growth, health, and neurodevelopment across the lifespan. Poor nutrition in this vulnerable period has irreversible consequences, including stunting, susceptibility to sickness, reduced school performance and productivity, and impaired intellectual and social development. UNICEF reported in 2018 that among the low cost flat residents in urban areas of the Klang Valley, 15% of children under 5 years old were stunted, 22% underweight, and 23% either overweight or obese. Will a micronutrient supplementation program improve the growth and iron status of children aged 6 months to 5 years staying in Lembah Subang? Children will be randomized into treatment and control groups. Treatment groups will receive dietary micronutrient supplementation packets. Measurements of height and weight and iron status will be taken at baseline and 4 months later.

NCT ID: NCT03771092 Completed - Clinical trials for Iron Deficiency Anemia

Comparing the Efficacy of Different Iron Formulations: Sucrosomal Ferric Pyrophosphate, SunActive®Fe and Intravenous Ferric Gluconate

Start date: November 2, 2015
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the effects of martial therapy, comparing different formulations, sucrosomal ferric pyrophosphate, SunActive®Fe micronized and ferric gluconate and different ways of administration, orally and intravenous, in subjects affected by sideropenic microcytic hypochromic anemia identified by the simultaneous presence of anemia, microcytosis and hypoferremia.

NCT ID: NCT03759353 Completed - Clinical trials for Iron Deficiency Anemia

Lactoferrin Versus Ferrous Sulfate in Iron-deficiency During Pregnancy

Start date: January 15, 2018
Phase: Phase 2
Study type: Interventional

The main drawbacks with oral iron are side-effects, poor compliance, and limited absorption from the gut. It has become very apparent gastrointestinal intolerance with oral iron therapy is dose related and common (up to 20% of patients), and this frequently leads to poor compliance. Lactoferrin (formerly known as lactotransferrin) is a glycoprotein, and a member of a transferrin family, thus belonging to those proteins capable of binding and transferring iron. It represents an attractive and promising alternative to ferrous sulphate oral administration as pregnant women receiving lactoferrin did not experience any adverse effects. This study aims to compare between lactoferrin and ferrous sulphate for therapy of iron deficiency in pregnant women.

NCT ID: NCT03749603 Completed - Anemia Clinical Trials

A Study Assessing Iron Status and Anemia in Filipino School Children From MIMAROPA Region

Start date: January 14, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the iron status and to confirm the usability of the non-invasive ZnPP measurement for screening the different stages of iron deficiency defined by standard measurements from blood.