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NCT05656157 Clinical Trial

Evaluation of a Clinical Decision Support System for Fungal Infections

Invasive Fungal Infections Clinical Trial

Official title:
Evaluation of a Clinical Decision Support System for the Treatment of Invasive Fungal Infections

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05656157
Other study ID # CRC_GHN_2022_001
Secondary ID
Status Completed
Phase
First received
Last updated
Start date December 1, 2022
Est. completion date November 30, 2023

Study information
Verified date April 2024
Source Hospices Civils de Lyon
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Invasive fungal infections are serious and frequent diseases in our hospitals, especially in intensive care units. In accordance with the institutional recommendations, it is necessary to have a clinical decision support system to support the clinicians in a rapid and optimal prescription of antifungals for invasive fungal diseases. This clinical decision support system will benefit patients but also clinicians who will gain in medical efficiency. It will also have an ethical dimension since it will guarantee optimal antifungal treatments for all patients. The purpose of the research is to define the percentage of concordance between the medical prescription and the recommendation of the clinical decision support system.

Recruitment information / eligibility
Status Completed
Enrollment 278
Est. completion date November 30, 2023
Est. primary completion date June 1, 2023
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - Patients receiving antifungal therapy for the treatment of invasive fungal disease Exclusion Criteria: - Patients not receiving antifungal therapy for the treatment of invasive fungal disease

Study Design

Related Conditions & MeSH terms

Intervention

Device:
• Medical device
Clinical decision support system

Locations
Country Name City State
France Hospices Civils de Lyon Lyon

Sponsors (1)
Lead Sponsor Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

References & Publications (2)

Bienvenu AL, Pavese P, Leboucher G, Berger P, Roux S, Charmillon A, Foroni L, Menotti J, Lebeaux D, Mayan R, Mondain V, Robin C, Lesprit P, Alfandari S, Kerneis S. Practical checklist for implementation of antifungal stewardship programmes. J Med Microbio — View Citation

Bienvenu AL, Pradat P, Guerin C, Aubrun F, Fellahi JL, Friggeri A, Guichon C, Hernu R, Menotti J, Monard C, Paulus S, Rimmele T, Piriou V, Chidiac C, Argaud L, Leboucher G. Evaluation of first-line therapies for the treatment of candidemia in ICU patients: A propensity score analysis. Int J Infect Dis. 2020 Apr;93:15-21. doi: 10.1016/j.ijid.2020.01.037. Epub 2020 Jan 23. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Percentage of concordance between the medical prescription and the recommendation of the clinical decision support system January to september 2023
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