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Intubation Complication clinical trials

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NCT ID: NCT06108271 Active, not recruiting - Cough Clinical Trials

Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal Injury

Triglotix®
Start date: October 1, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial is to compare two different orotracheal tubes in patients which require orotracheal intubation for general anesthesia. The main questions it aims to answer are: - To assess the presence of laryngeal injury - To evaluate the consequences in voice quality - To ask for the presence of symptoms as sore throat, hoarseness, and cough Participants will be randomly assigned into two groups, one will use conventional endotracheal tube and the other will use Triglotix® endotracheal tube.

NCT ID: NCT06085326 Recruiting - Clinical trials for Intubation Complication

Smart Checklist Implementation for Pediatric Tracheal Intubations in the ICU- Multicenter Study

SMART PICU
Start date: October 1, 2023
Phase: N/A
Study type: Interventional

The purpose of the study is to implement a patient-provider dyad tailored, Electronic Health Record (EHR)-informed, digitized Smart Checklist as a Quality Improvement (QI) intervention to support bedside clinician teams to reduce Adverse Airway Outcomes (AAO) across 6 diverse pediatric intensive care units (ICUs).

NCT ID: NCT06065956 Completed - Clinical trials for Intubation Complication

Comparison of Hemodynamic Changes With Morphine Versus Esmolol During Induction of Anaesthesia

Start date: August 28, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Comparing hemodynamic changes with morphine versus esmolol as an adjuvant agent during induction of Anaesthesia

NCT ID: NCT05983666 Recruiting - Clinical trials for Intubation Complication

POCUS ASSESSMENT FOR TRACHEAL VS OESOPHAGEAL INTUBATION

PATO
Start date: July 1, 2023
Phase:
Study type: Observational

The clinical importance of airway management has gained prominence in the last decade in most scientific societies with the aim of improving the standard of care. The WHO has focused guidelines for "Safety in Surgery", which attempt to encompass all methods that predict and recognise airway management risk and should be applied by the surgical team, and has therefore created and implemented a surgical checklist that can be useful in reducing the risk of unidentified difficulties. The same suggestion has been included in the Helsinki Declaration on Patient Safety in Anaesthesiology, signed by most European entities in cooperation with the European Society of Anaesthesiology (ESA), the European Board of Anaesthesiology (EBA-UEMS), and the World Federation of Societies of Anaesthesiology (WFA). Confirmation of correct endotracheal tube (ET) placement is a crucial step in airway management, as unrecognised oesophageal intubation can have catastrophic consequences. Numerous methods are used to verify correct ET placement, including visual confirmation of tube passage through the vocal cords during laryngoscopy, chest wall expansion during ventilation, visualisation of the tracheal rings and carina using a flexible bronchoscope, auscultation, capnometry, capnography and chest radiography. These techniques vary in their degree of precision. Although capnography is considered the gold standard for confirming tracheal intubation, it has some important limitations. In recent years, ultrasonography has been introduced as the fifth pillar of the physical examination of the patient: inspection, palpation, percussion, auscultation and insonation. For airway assessment and management, Point-of-Care UltraSound (PoCUS) has been incorporated into routine clinical practice, answering open diagnostic questions, aiding in differential diagnosis and guiding procedures. Thus, investigators propose a simple, quick and easy-to-learn approach for the interpretation of ultrasound imaging findings during airway management.

NCT ID: NCT05960929 Not yet recruiting - Clinical trials for Intubation Complication

InfasurfAeroâ„¢ Versus Sham Treatment in Preterm Newborns With RDS

Aero-05
Start date: April 1, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAeroâ„¢, a novel oral airway delivery device specifically designed to give Infasurf in a less complicated way and without the need for a breathing tube or interrupting nasal respiratory support.

NCT ID: NCT05954533 Recruiting - Clinical trials for Intubation Complication

HEAVEN CRITERIA vs Modified LEMON Score for Predicting Difficult Intubation

Start date: July 1, 2022
Phase:
Study type: Observational

Emergency tracheal intubation is a lifesaving procedure frequently performed on critically ill and injured patients in the emergency department (ED). Emergency intubations are more difficult than elective intubations in the operating room setting because of the sicker patient population with a limited physiologic reserve and less controlled setting in the ED. Indeed, the proportion of difficult intubation ranges from 10% to 27% in the ED setting , whereas the rate ranges from 1% to 9% of elective intubation in the anaesthesia setting. Because emerging evidence demonstrates that repeated intubation attempts are associated with an increased risk of adverse events, early recognition of difficulty intubation with a systematic use of rescue methods in ED patients is critical. The commonest airway prediction tool is the LEMON score. In the modified LEMON score "Mallampati" was excluded as it was not a pragmatic assessment in the ED. Existing difficult airway prediction tools were derived in the elective surgery environment and may not be applicable to emergency airway management. LEMON criteria was designed for preoperative clinical setting. Hence in this study we are observing if HEAVEN (H- Hypoxemia E - extremes of age A - anatomical abnormalities V - vomit/ blood / fluid E - Exsanguination/anaemia N - neck mobility issues) is a better tool for predicting difficult intubatio.

NCT ID: NCT05884645 Active, not recruiting - Clinical trials for Intubation Complication

Video Intelligence intubaTION (VITION)

VITION
Start date: May 1, 2023
Phase:
Study type: Observational

This study aims to train an AI for video-directed endotracheal intubation (VITION) to recognise the anatomical structures of the upper airway during video-directed endotracheal intubations.

NCT ID: NCT05850260 Recruiting - Clinical trials for Intubation Complication

McGrath Video Laryngoscope for All Intubations in the Operating Room

VIDEO-SURG
Start date: June 1, 2023
Phase:
Study type: Observational [Patient Registry]

Tracheal intubation is a very common procedure performed in the operating room. The usual intubation technique in the operating room is based on direct laryngoscopy, using a standard Macintosh laryngoscope. Although in most patients there are no complications during intubation, more than 90% of difficult tracheal intubations in the operate room are unpredictable, and several authors, recommend the universal use of the videolaryngoscope for all intubations, using as the first intubation option regardless of whether the patient has predictors of a difficult airway or no.The authors do not know whether providing a own videolaryngoscope to each anesthesiologist to use as the first option for intubation in all patients who need it in the operating room improves the percentage of patients with easy intubation and decrease the incidence of complications.

NCT ID: NCT05838690 Recruiting - Clinical trials for Intubation Complication

Optimizing Tracheal Intubation Outcomes and Neonatal Safety

OPTION SAFE
Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The purpose of the study is to assess the impact of a personalized intubation planning tool, the Personalized INtubation Safety (PINS) Bundle on intubation procedural safety and clinical outcomes among patients intubated in the neonatal intensive care unit (NICU) setting.

NCT ID: NCT05804188 Recruiting - Clinical trials for Intubation Complication

CRICKET: Critical Events in Anaesthetised Kids Undergoing Tracheal Intubation

CRICKET
Start date: January 8, 2024
Phase:
Study type: Observational [Patient Registry]

The investigators' overall objective is to assess the incidence of critical events related to tracheal intubation at all international study sites. Furthermore, the study will investigate the used intubation techniques and identify possible improvement measures to increase patient safety.