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Intubation Complication clinical trials

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NCT ID: NCT06401486 Not yet recruiting - Anesthesia Clinical Trials

DOuble-Lumen Intubation With VIdeolaryngoscopy

DoLVi
Start date: June 1, 2024
Phase: N/A
Study type: Interventional

Tracheal intubation (TI) is one of the fundamental and most recognized techniques in Anesthesiology, also essential in all units treating urgent pathology and critical patients. It involves advancing a tube through the vocal cords into the trachea to ventilate the patient. In thoracic surgery, it is often necessary to achieve lung isolation, ventilating only one lung while the operated lung remains collapsed and immobile. To achieve this, it is common to intubate the patient with a special tube: a double-lumen tube (DLT), larger than usual because it provides two ventilation channels, one for each lung. Tracheal intubation with a DLT presents some peculiarities: its larger size and stiffness make manipulation and orientation in the oropharynx difficult. It has a curve at its distal end (the bronchial lumen) designed to slide into the left or right main bronchus as needed. The fact that the DLT passes between the vocal cords does not ensure its proper placement and function. Therefore, DLT intubation requires practice and experience, both to slide it between the vocal cords and to position it properly. The classic technique for DLT intubation is "Direct Laryngoscopy" (DL). A traditional laryngoscope with a Macintosh blade is used to move the upper airway structures aside to allow direct visualization of the glottis. In recent years, to facilitate tracheal intubation, different videolaryngoscopes have appeared. A videolaryngoscope is a device similar to a traditional laryngoscope that allows, thanks to an image sensor located at its end, indirect visualization of the glottis on an integrated or external screen. There is strong evidence for the benefit of using a VL over traditional DL in single-tube intubation in adult patients. However, although the use of VL for DLT intubation is becoming more common, there are few studies with small sample sizes comparing VL to DL for DLT intubation, so the evidence of its advantages or disadvantages is of low quality. It could improve glottic exposure and the percentage of success on the first attempt, although there is a possibility of increased tube malposition incidence and delayed intubation. Therefore, Investigators propose a prospective, multicenter, randomized study comparing the traditional Macintosh blade laryngoscope (direct laryngoscopy) with the videolaryngoscope to facilitate orotracheal intubation with double-lumen tube in patients scheduled for thoracic surgery requiring lung isolation.

NCT ID: NCT06297720 Not yet recruiting - Anesthesia Clinical Trials

Early Oral Hydration After Thoracoscopic Surgery

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn about the safety and feasibility of early oral hydration in patients receiving video-assisted thoracoscopic surgery after general anesthesia. The main questions aims to answer: - the safety and feasibility of oral hydration supplementation in the recovery room following general anesthesia. - the degree of improvement in sore throat and dry mouth after oral hydration. - the side effects and risks of oral hydration supplementation, such as the incidence of postoperative nausea and vomiting. - the impact of oral hydration supplementation in the recovery room following general anesthesia on hemodynamics. - patient satisfaction with oral hydration supplementation in the recovery room following general anesthesia. Participants will receive a series of oral hydration from swab moistening, and ice cube hydration to water hydration in the recovery room. Researchers will compare with the standard, no-hydration group to see if it is safe and feasible to hydrate patients in the recovery room.

NCT ID: NCT06232837 Not yet recruiting - Clinical trials for Intubation Complication

Macintosh Blade Size for Endotracheal Intubation in Operative Rooms

MacSize_OR
Start date: February 1, 2024
Phase:
Study type: Observational

Endotracheal intubation is a frequent procedure in the operating room but optimal Macintosh blade size remains unknown to date.

NCT ID: NCT06210867 Not yet recruiting - Clinical trials for Intubation Complication

Factors Associated With Occluding the Upper Esophagus by Paratracheal Force

Start date: February 27, 2024
Phase:
Study type: Observational

We aim to identify anatomical factors that affect upper esophageal occlusion during the application of paratracheal pressure.

NCT ID: NCT06113939 Not yet recruiting - Cardiac Arrest Clinical Trials

Prevention of Infection of the Respiratory Tract Through Application of Non-Invasive Methods of Secretion Suctioning

PIRAMIDES
Start date: July 2024
Phase: N/A
Study type: Interventional

Severe trauma, head trauma, stroke and resuscitated cardiac arrest patients requiring endotracheal intubation and mechanical ventilation are at high risk of early-onset ventilator-associated pneumonia (EO-VAP). A short course of systemic antibiotic is recommended for prophylaxis. This study intends to assess the safety and efficacy of 2 alternative mechanical non-invasive airway clearance techniques in the prevention of EO-VAP in an open label randomized pilot trial of 20 subjects per study group i.e., 60 cases. The interventions will be in place for 7 days and the observational periods will be 14 days.

NCT ID: NCT05960929 Not yet recruiting - Clinical trials for Intubation Complication

InfasurfAeroâ„¢ Versus Sham Treatment in Preterm Newborns With RDS

Aero-05
Start date: July 1, 2024
Phase: Phase 3
Study type: Interventional

The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAeroâ„¢, a novel oral airway delivery device specifically designed to give Infasurf in a less complicated way and without the need for a breathing tube or interrupting nasal respiratory support.

NCT ID: NCT05659212 Not yet recruiting - Clinical trials for Intubation Complication

Block Pressor Response to Intubation

Start date: January 3, 2023
Phase: N/A
Study type: Interventional

Laryngoscopy and endotracheal intubation are necessary for effective control of airway and ventilation, but it has deleterious effects such as hypertension and disrhythmia

NCT ID: NCT05445271 Not yet recruiting - Clinical trials for Intubation Complication

Optic Nerve Sheath Diameter in Pediatric Patients

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Endotracheal intubation and laryngeal mask are generally applied to secure the airway during general anesthesia. There is a widespread opinion among anesthesiologists that endotracheal intubation increases intracranial pressure. Since there were no non-invasive methods measuring intracranial pressure in the past, adequate studies on this subject could not be done. With this measurement, we aimed to show whether ETT or LMA applications have effects on intracranial pressure.

NCT ID: NCT05317156 Not yet recruiting - Dysphagia Clinical Trials

The Effect of Cold Vapor on Intubation-Related Symptoms and Comfort in the Early Postoperative Period

Start date: April 18, 2022
Phase: N/A
Study type: Interventional

Endotracheal Intubation (EI) is performed in order to monitor the effectiveness of anesthesia and to control the patient's breathing during the surgery under general anesthesia. In EI, which is an invasive procedure, damage to the larynx and trachea may occur during the placement of the endotracheal tube or due to long-term use. Complications such as postintubation ulcer, laryngeal nerve paresis, arytenoid dislocation may develop in the early period due to EI, and patients may have complaints such as sore throat, swallowing problems, hoarseness, and cough in the postoperative period. This affects the comfort of the patients in the postoperative period. For this reason, it is important to prevent intubation-related symptoms of patients who will undergo surgical intervention before they occur.

NCT ID: NCT05036460 Not yet recruiting - Ultrasonography Clinical Trials

Real-time Sonography in Detecting Inadvertent Esophageal Intubation Among Difficult Intubation Patients

SDEIDI
Start date: September 20, 2021
Phase: N/A
Study type: Interventional

Early detection of esophageal intubation, one of the most common complications while performing endotracheal intubation (ETI), is crucial to adequate airway management, especially among patients suspected of difficult intubation (DI). Detective approaches with ventilation require time, increase the risk of emesis and aspiration to patients, and increase the risk of particle aerosolization to health providers under the epidemic of aerosol-borne diseases. Our study will determine the effectiveness of real-time sonography assisted to direct visualization to detect esophageal intubation before ventilation among DI patients.