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Intraoperative Hypotension clinical trials

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NCT ID: NCT05425147 Recruiting - Clinical trials for Intraoperative Hypotension

Correlation Between Perioperative Autonomic Function and Post-induction Hypotension in Elderly Patients

Start date: July 25, 2022
Phase:
Study type: Observational

Elderly patients have a higher risk of post-induction hypotension (PIH). The decreased cardiovascular autonomic function at baseline in elderly patients may contribute to the development of PIH. The objective of our study is to effect of preoperative cardiovascular autonomic modulation in PIH, we will recruit elderly patients who are going to have general anesthesia surgery and measure preoperative baroreflex sensitivity (BRS) and heart rate variability (HRV). The primary outcome will be PIH. Secondary outcomes included: early intraoperative hypotension, postoperative complications, and 30-day postoperative mortality.

NCT ID: NCT05341167 Recruiting - Clinical trials for Intraoperative Hypotension

HPI Algorithm for the Prevention of IOH During Spinal Surgery [HPIFPIOH]

HPIFPIOH
Start date: June 6, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the hypothesis that the use of the Hypotension Prediction Index algorithm (HPI) can reduce intraoperative hypotension (IOH) in adult patients undergoing spinal surgery in the prone position under general anesthesia, as well as to explore its effect on in-hospital postoperative morbidity and mortality.

NCT ID: NCT05011357 Recruiting - Clinical trials for Intraoperative Hypotension

Phenylephrine and Pulse Pressure Variability

Start date: September 10, 2021
Phase: Early Phase 1
Study type: Interventional

The purpose of this research study is to determine how vasopressors affect a measure of how intravenous fluid is administered in people undergoing surgery who have low blood pressure called Pulse Pressure Variability (PPV). This study will recruit human subjects to undergo simulated hypovolemia called Lower Body Negative Pressure (LBNP) and will receive phenylephrine and placebo, while PPV will be measured in both conditions. This research will help anesthesiologists learn more about how to use PPV in patients undergoing surgery and who need vasopressors.

NCT ID: NCT04872504 Recruiting - Clinical trials for Intraoperative Hypotension

Hypotension Prediction Index in Patients Undergoing Liver Transplantation

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

A prospective, open-label and single-center study to determine whether the use of Acumen Hypotension Prediction Index software predicts the occurrence of hypotension.

NCT ID: NCT04697498 Recruiting - Chronic Pain Clinical Trials

Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations

BBESPB
Start date: December 16, 2020
Phase: N/A
Study type: Interventional

Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain. Development and implementation in clinical practice perioperative intensive care protocols for surgical correction of spinal deformities.

NCT ID: NCT04483765 Recruiting - Geriatrics Clinical Trials

Shock Index, Modified Shock Index and Age-related Shock Index for Predicting Post-spinal Hypotension in Elderly Patients

Start date: July 1, 2020
Phase:
Study type: Observational

Aim of this prospective observational study is to investigate whether shock index(SI), modified shock index(MSI) and age related shock index(ASI) have any predictive value in predicting post-spinal hypotension which may develop in patients over 65 years of age, who are planned to undergo transurethral resection of the prostate (TURP) and transurethral resection of the bladder (TURB) surgery under spinal anesthesia.

NCT ID: NCT04120012 Recruiting - Clinical trials for Perioperative Complication

The Effect of Frailty to Perioperative Complications in the Elderly

Start date: November 20, 2019
Phase:
Study type: Observational

With the progression of population aging, the number of elderly patients undergoing surgery is increasing as well. However, as the condition of health differs greatly between individual elderly patients even of the same age, it is a necessity to evaluate elderly patients thoroughly and individually for better management of perioperative care. Frailty is a condition in which patients are impaired at physical reserve and homeostatic control. Frail elderly people are at higher risk of morbidity and mortality after exposure to a stressor. Frail patients are at higher risk of perioperative complications and longer hospital stay. However, there has been no standard criteria or tool to evaluate frailty in the elderly. Neither has there been enough evidence explaining the mechanism between frailty and increased perioperative complications. Therefore, in this study we aim to discover the relationship between frailty and intraoperative hemodynamic instability, as well as perioperative complications in the elderly patients, hoping to find an adequate and practical model for preoperative assessment in the elderly hopefully for better perioperative outcome.

NCT ID: NCT04117867 Recruiting - Clinical trials for Perioperative Complication

The Association Between Intraoperative Hypotension and Perioperative Stroke

Start date: December 30, 2019
Phase:
Study type: Observational

The aim of this study is to investigate the association between the severity and duration of intraoperative hypotension and the incidence of perioperative stroke after non-cardiac and non-neurologic surgeries.The secondary aim of this study is to confirm the potential risk factors of the perioperative stroke.

NCT ID: NCT03795831 Recruiting - Clinical trials for Intraoperative Hypotension

Validation Study in Patients of a Non-invasive Blood Pressure Monitor for Perioperative Use

Start date: March 1, 2017
Phase:
Study type: Observational [Patient Registry]

Collecting all available data (waveforms, beat to beat data, status data) generated by a non invasive blood pressure monitor on each hand and compare this to the actual data obtained by intra arterial (radial) monitoring. This to see if the non invasive bloodpressure monitor can be validated for intraoperative use.

NCT ID: NCT03629418 Recruiting - Acute Kidney Injury Clinical Trials

Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery

Start date: August 14, 2018
Phase: N/A
Study type: Interventional

Acute renal injury (AKI) is a common complication after cardiac surgery and is associated with worse outcomes. It is now realized that intraoperative hypotension is an important risk factor for the development of AKI. In a recent randomized controlled trial of patients undergoing major noncardiac surgery, intraoperative individualized blood-pressure management reduced the incidence of postoperative organ dysfunction. The investigators hypothesize that, for patients undergoing off-pump CABG, targeted blood-pressure management during surgery may also reduce the incidence of postoperative AKI.