Clinical Trials Logo
  1. Home
  2. Intraoperative Bleeding
  3. NCT06264596
  4. Details
NCT06264596 Clinical Trial

Epinephrine in Irrigation Fluid for Visualization During Ankle Surgery

Intraoperative Bleeding Clinical Trial

Official title:
The Effect of Epinephrine in Irrigation Fluid for Visualization During Ankle Arthroscopy: A Randomized Blinded Controlled Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT06264596
Other study ID # 2310-72
Secondary ID
Status Not yet recruiting
Phase Phase 3
First received
Last updated
Start date April 2024
Est. completion date April 2026

Study information
Verified date February 2024
Source The Guthrie Clinic
Contact Wonyong Lee, MD
Phone 570-887-4882
Email wonyong.lee@guthrie.org
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to evaluate the effect of epinephrine in irrigation fluid for visual clarity in ankle arthroscopic surgery.

Description:

The primary outcomes are: - visual clarity during ankle arthroscopic surgery, which will be evaluated by visual analog scale from 0-10, - and the intraoperative surgeon's discomfort related to bleeding, that will be measured by visual numeric rating scale from 0-3.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 78
Est. completion date April 2026
Est. primary completion date April 2025
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Males and Females ages over 18 years - Patients who undergo ankle arthroscopic surgery - Patients who are able to read and give informed consent on their own behalf Exclusion Criteria: - Patients with any known cardiac diseases - Uncontrolled hypertension (> 180/110 mmHg) - Revision case - Younger than 18 years of age - Pregnant women

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Epinephrine
The epinephrine group will have two 3-L normal saline solution bags prepared for each case with 1 mL of 1:1000 epinephrine in each bag
Procedure:
• Normal Saline irrigation fluid
The control group will have two 3-L normal saline solution bags prepared with no additive

Locations
Country Name City State
United States Robert Packer Hospital Sayre Pennsylvania

Sponsors (1)
Lead Sponsor Collaborator
The Guthrie Clinic

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary visual clarity during ankle arthroscopic surgery, which will be evaluated by visual analog scale visual analog scale from 0-10 intraoperative
Primary surgeon's discomfort related to bleeding, measured by visual numeric rating scale visual numeric rating scale 0-3 intraoperative
See also
  Status Clinical Trial Phase
Recruiting NCT05900037 - GATT-Patch Versus SURGICEL® Original in Minimally Invasive Liver and Gallbladder Surgery N/A
Recruiting NCT04609410 - Bleeding in Laparoscopic Liver Surgery N/A
Terminated NCT01458561 - Adjunctive Application of BioFoam Surgical Matrix in Liver Surgery Phase 3
Completed NCT01656759 - Use of a Novel Fibrin Sealant in Total Knee Arthroplasty Phase 2/Phase 3
Completed NCT01651806 - Weighted Versus Uniform Dose of Tranexamic Acid in Patients Undergoing Primary, Knee Arthroplasty Phase 2/Phase 3
Completed NCT05867342 - Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery Phase 4
Not yet recruiting NCT05841251 - Phenylephrine Versus Tranexamic Acid to Control Bleeding in Patients Undergoing Inferior Turbinoplasty by Coblation N/A
Not yet recruiting NCT06450834 - Ostene in Thoracolumbar Decompression and Fusion Evaluated With VIBE
Not yet recruiting NCT06427707 - The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries. Phase 2/Phase 3
Active, not recruiting NCT01539057 - The Efficacy of the Administration of Fibrinogen in Liver Transplantation Phase 3
Completed NCT03820206 - The Value of Tranxemic Acid to Reduce Intraoperative Blood Loss During Elective Cesarean Sections in High Risk Women N/A
Completed NCT01891461 - Study to Compare the Addition of Floseal to Our Standard of Care to Control Post Operative Bleeding in TKR Phase 4
Completed NCT03047070 - Lidocaine in ERAS for FESS Phase 2
Completed NCT04188184 - Tranexamic Acid Versus Epinephrine During Exploratory Tympanotomy N/A
Recruiting NCT04697498 - Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations N/A
Completed NCT05385952 - GATT-Patch Versus TachoSil in Liver Surgery N/A
Completed NCT02229292 - Prevention of Intraoperative Bleeding and Postoperative Swelling in Orthognathic Surgery Through the Use of Tranexamic Acid Phase 4
Recruiting NCT03112135 - Effect of Topical and Systemic Tranexemic Acid on Bleeding During Ear Exploration Surgery Phase 2
Recruiting NCT06399445 - Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants Phase 4