Intractable Epilepsy Clinical Trial
Official title:
The Impact of Reducing Overtreatment on Quality of Life in Children With Refractory Epilepsy
The primary aim of the study is to determine the effect of reducing the number and/or dose
of anti epileptic drugs on an individual's quality of life and seizure control in people
with difficult to control epilepsy and who are on polytherapy.
This is a randomised trial so children will be divided into two groups, with reduction of
anti epileptic drugs in the first group (withdrawal group) and no change to their
medications in the second (control group). Irrespective of the group the child is assigned
to (withdrawal group or control group), we will ask parents to complete several
questionnaires on 2 occasions: the first time will be immediately after the child enters the
study (i.e. baseline assessment), and a second and last one will be 6 months after entering
the study (i.e. follow-up assessment). These questionnaires aim to "quantify" aspects
related with quality of life, AED side effects, seizure severity, and behaviour.
n/a
Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Single Blind (Investigator)
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