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Clinical Trial Summary

The goal of this clinical trial is to compare intracranial aneurysm patients. The main question it aims to answer are: Which heparinization regimen is most beneficial to patients during surgery for intracranial aneurysms. Participants will be randomized to different intraoperative heparinization regimens: (i) 50 U/kg intravenous (IV) at 1-h intervals reduced by half to a minimum of 1000 u/h; (ii) 70 U/kg IV at 1-h intervals reduced by half to a minimum of 1000 u/h. MRI will be performed within 72 h after surgery, and the DWI sequence of MRI will be analyzed. If there is a comparison group: Researchers will compare different intraoperative heparinization protocol groups to see which dose of intraoperative heparin has the best prognosis for use.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05749393
Study type Interventional
Source The First Affiliated Hospital with Nanjing Medical University
Contact Hua Lu, Doctor
Phone 18761671021
Email luhua@njmu.edu.cn
Status Recruiting
Phase N/A
Start date April 30, 2023
Completion date April 1, 2024

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