Critically Ill Clinical Trial
Official title:
The Effects of Various PEEP (Positive End-expiratory Pressure) Levels on Intraabdominal Pressure and Hemodynamics in Critically Ill Patients
In this study, it was aimed to compare the effects of three different PEEP levels (0-4, 5-8, 9-12 cmH2O) on intraabdominal pressure and hemodynamic parameters of patients in intensive care unit.
Patients between 18-80 years old whom were mechanically ventilated without any spontaneous
respiratory efforts on supine position were included into the study. Bladder pressure
measurement as a practical and frequently preferred method was used in order to measure
intra-abdominal pressure. 100 ml isotonic fluid was given during the measurement. Level of
symphysis pubis was chosen for zeroing the pressure transducer to measure the intra-abdominal
pressure.
Three patient groups, each containing 22 cases, totally 66 patients were planned in this
study. All patients were mechanically ventilated with various PEEP levels. The patients with
0-4 cmH2O PEEP levels were named Group 4; the patients with 5-8 cmH2O PEEP levels were named
Group 8; the patients with 9-12 cmH2O PEEP levels were named Group 12. The levels of
patients' PEEP levels were arranged by the responsible intensive care physician regarding to
the patients' clinic.
Intraabdominal, central venous, arterial blood pressures, pulse rates, peripheric oxygen
saturation, body temperature, instant fluid balances and amounts of urine (in ml/kg/hour
unit) of the patients were measured on the 0. 6. 12. 18. and 24. hours and recorded.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05539521 -
Efficacy and Safety of Remimazolam Besylate Versus Propofol for Sedation in Critically Ill Patients With Deep Sedation
|
Phase 2 | |
| Recruiting |
NCT04776486 -
Iohexol Clearance in Critically Ill Patients With Augmented Renal Creatinine Clearance
|
N/A | |
| Recruiting |
NCT05766319 -
The ICU-recover Box, Using Smart Technology for Monitoring Health Status After ICU Admission
|
N/A | |
| Recruiting |
NCT03231540 -
The PREServation of MUScle Function in Critically Ill Patients (PRESMUS)
|
N/A | |
| Completed |
NCT02286869 -
Cardioventilatory Coupling in Critically Ill Patients
|
N/A | |
| Completed |
NCT01434823 -
24 Hour Intensivist Coverage in the Medical Intensive Care Unit
|
N/A | |
| Active, not recruiting |
NCT01142570 -
Effect of Enteral Nutrition Enriched in Protein and Based on Indirect Calorimetry Measurement in Chronically Critically Ill Patients
|
N/A | |
| Completed |
NCT01167595 -
Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients
|
N/A | |
| Completed |
NCT01293708 -
Realities, Expectations and Attitudes to Life Support Technologies in Intensive Care for Octogenarians:
|
||
| Not yet recruiting |
NCT00916591 -
Prokinetic Drugs and Enteral Nutrition
|
N/A | |
| Recruiting |
NCT00654797 -
Improving Blood Glucose Control With a Computerized Decision Support Tool: Phase 2
|
Phase 2 | |
| Withdrawn |
NCT00178321 -
Improving Sleep in the Pediatric Intensive Care Unit
|
N/A | |
| Completed |
NCT01168128 -
PERFormance Enhancement of the Canadian Nutrition Guidelines by a Tailored Implementation Strategy: The PERFECTIS Study
|
N/A | |
| Completed |
NCT02447692 -
Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The PROMIZING Study
|
N/A | |
| Recruiting |
NCT04582760 -
Early Mobilization in Ventilated sEpsis & Acute Respiratory Failure Study
|
N/A | |
| Not yet recruiting |
NCT05961631 -
Bio-electrical Impedance Analysis Derived Parameters for Evaluating Fluid Accumulation
|
||
| Completed |
NCT03276650 -
Admission of Adult-onset Still Disease Patients in the ICU
|
||
| Completed |
NCT03922113 -
Muscle Function After Intensive Care
|
||
| Recruiting |
NCT05055830 -
Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)
|
||
| Recruiting |
NCT06027008 -
Mechanical Insufflation-Exsufflation (Cough Assist) in Critically Ill Adults
|
N/A |