Critical Illness Clinical Trial
Official title:
Incidence and Prognostic Significance of Intraabdominal Pressure in Critically Ill Patients
This study is conducted to evaluate the incidence and prognostic significance of IAH in medical ICU patients.
Increased Intra-abdominal pressure (IAP) is an important cause of morbidity and mortality in
ICU patients with consequent pulmonary, hepatic, central nervous and renal system
impairments.
The increase in IAP is rarely diagnosed in ICU and the lack of diagnosis of this condition
may lead to the worsening of patient prognoses because of retardation of appropriate
interventions .
The current literatures show conflicting cutoff values of IAP that predict AKI, possibly due
to the fact that many studies were conducted before publishing of the first Consensus of
IAH/ACS, which standardized the measurement method of IAP.
Intra-abdominal hypertension is defined as a sustained or repeated pathologic elevation of
intra-abdominal pressure greater than 12 mmHg [Malbrain et al 2004, cheathamML et al 2007].
Intra-abdominal hypertension is graded as follows:
- Grade I Intra-abdominal pressure 12-15 mmHg.
- Grade II Intra-abdominal pressure 16-20 mmHg.
- Grade III Intra-abdominal pressure 21-25 mmHg.
- Grade IV Intra-abdominal pressure greater than 25 mmHg Various risk factors contribute
to the development of IAH in medical ICU including; massive fluid resuscitation (> 3500
ml/24 h), ileus, respiratory, renal, or liver dysfunction, hypothermia, acidosis,
anemia, oliguria, and hyperlactatemia .
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04551508 -
Delirium Screening 3 Methods Study
|
||
| Recruiting |
NCT06037928 -
Plasma Sodium and Sodium Administration in the ICU
|
||
| Completed |
NCT03671447 -
Enhanced Recovery After Intensive Care (ERIC)
|
N/A | |
| Recruiting |
NCT03941002 -
Continuous Evaluation of Diaphragm Function
|
N/A | |
| Recruiting |
NCT04674657 -
Does Extra-Corporeal Membrane Oxygenation Alter Antiinfectives Therapy Pharmacokinetics in Critically Ill Patients
|
||
| Completed |
NCT04239209 -
Effect of Intensivist Communication on Surrogate Prognosis Interpretation
|
N/A | |
| Completed |
NCT05531305 -
Longitudinal Changes in Muscle Mass After Intensive Care
|
N/A | |
| Terminated |
NCT03335124 -
The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock
|
Phase 4 | |
| Completed |
NCT02916004 -
The Use of Nociception Flexion Reflex and Pupillary Dilatation Reflex in ICU Patients.
|
N/A | |
| Recruiting |
NCT05883137 -
High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill
|
||
| Completed |
NCT04479254 -
The Impact of IC-Guided Feeding Protocol on Clinical Outcomes in Critically Ill Patients (The IC-Study)
|
N/A | |
| Recruiting |
NCT04475666 -
Replacing Protein Via Enteral Nutrition in Critically Ill Patients
|
N/A | |
| Not yet recruiting |
NCT04516395 -
Optimizing Antibiotic Dosing Regimens for the Treatment of Infection Caused by Carbapenem Resistant Enterobacteriaceae
|
N/A | |
| Not yet recruiting |
NCT04538469 -
Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and Staff
|
||
| Withdrawn |
NCT04043091 -
Coronary Angiography in Critically Ill Patients With Type II Myocardial Infarction
|
N/A | |
| Recruiting |
NCT02989051 -
Fluid Restriction Keeps Children Dry
|
Phase 2/Phase 3 | |
| Recruiting |
NCT02922998 -
CD64 and Antibiotics in Human Sepsis
|
N/A | |
| Completed |
NCT03048487 -
Protein Consumption in Critically Ill Patients
|
||
| Completed |
NCT02899208 -
Can an Actigraph be Used to Predict Physical Function in Intensive Care Patients?
|
N/A | |
| Recruiting |
NCT02163109 -
Oxygen Consumption in Critical Illness
|