Interstitial Lung Disease Clinical Trial
Official title:
Assessment of Lung Movement With CT in Healthy Subjects and Patients With ILD
NCT number | NCT03068091 |
Other study ID # | 2006114 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | July 1, 2017 |
Est. completion date | October 31, 2018 |
Verified date | April 2020 |
Source | University of Missouri-Columbia |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to determine whether patient with ILD have altered lung compliance on chest CT before they have macroscopic structural changes on CT.
Status | Completed |
Enrollment | 25 |
Est. completion date | October 31, 2018 |
Est. primary completion date | September 30, 2018 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Subjects with ILD: Subjects must have a physician diagnosis of ILD and be in stable pulmonary condition at the time of the CT - Healthy subjects: Subjects must have no history of pulmonary disease and smoked less than 100 cigarettes in their lifetime Exclusion Criteria: - Subjects less than 18 years of age |
Country | Name | City | State |
---|---|---|---|
United States | University of Missouri-Columbia | Columbia | Missouri |
Lead Sponsor | Collaborator |
---|---|
University of Missouri-Columbia | Henry M. Jackson Foundation for the Advancement of Military Medicine |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Lung Motion as Assessed by CT | A computer algorithm will compare the inspiration and expiration CT scans to determine regional lung motion. | Study visit 1 of a single visit study | |
Secondary | Lung Motion: Lobar Strain Which is a Ratio | Lobar strain (S): the volumetric strain of each lobe i [i = Right Upper (RU), Right Lower (RL), Left Lower (LL), and Left Upper (LU)] as the difference in lobe volume between the expanded and contracted states, normalized by the lobe volume in the expanded state | Study visit 1 of a single visit study |
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