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Clinical Trial Summary

Our goal is to determine the cellular scale changes that occur in subjects who have disease progression due to pentosan polysulfate sodium toxicity


Clinical Trial Description

The aim of this study is to determine the formation and progression of retinal changes caused by pentosan polysulfate sodium toxicity. To do this, we will measure how single cone photoreceptors respond to light in regions of the retina that are affected by pentosan polysulfate sodium toxicity. We will also measure how the retinal pigment epithelium, a layer of cells vital to photoreceptor health, change in shape and size over time. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05643157
Study type Observational
Source Indiana University
Contact Kristen Bowles Johnson, O.D.,Ph.D.
Phone 812-855-8991
Email kbowlesj@iu.edu
Status Recruiting
Phase
Start date November 1, 2022
Completion date September 30, 2024

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