Light Therapy for Internet Gaming Disorder

Internet Gaming Disorder Clinical Trial

Official title:

A Randomized Controlled Double-Blind Trial of Light Therapy for Internet Gaming Disorder

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06165549
• Other study ID #: Internet Gaming Disorder
• Status: Recruiting
• Phase: N/A
• Start date: December 16, 2023
• Est. completion date: August 31, 2024

Study information

• Verified date: December 2023
• Source: Jinan University Guangzhou
• Contact: Qian Tao, phD
• Phone: +8618818879657
• Email: hhyang12138[@]163.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This project aims to investigate (1) the efficacy of light therapy on internet gaming disorder (IGD); (2) the underlying neural mechanisms of such efficacy

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 90
• Est. completion date: August 31, 2024
• Est. primary completion date: April 30, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 28 Years

Eligibility

Inclusion Criteria:

1. the 5th edition of Diagnostic and Statistical Manual of Mental Disorders (DSM-5 ) recommended diagnosis of Internet gaming disorder;

2. the scores of the Young-Internet addiction Test = 50;

3. playing internet games =20 h/week for =1 year

Exclusion Criteria:

1. current or history of psychiatric or neurological illness;

2. current or history of use of illegal substances and other addictions;

3. current use of psychotropic medications ;

4. any history of head trauma, presence of metal in the body or other contraindication to functional MRI scanning

Related Conditions & MeSH terms

• Internet Gaming Disorder
• Light Therapy

Intervention

Other:
• Light therapy
The light therapy will be administered by custom-made light boxes (LED) with adjustable brightness. The light intensity will be set at 5000 Lux. The intervention will consist of daily exposure for 30 minutes in the morning. The whole intervention includes 14±5 days.
• Light placebo therapy
The light placebo intervention will be administered by custom-made light boxes (LED) with adjustable brightness. The light intensity will be set at less than 200 Lux. The intervention will consist of daily exposure for 30 minutes in the morning. The whole intervention includes 14±5 days.
• Emotion Bias Modification Training
The training aims at associating gaming pictures with negative words and pictures of healthy activities with positive words. Gaming pictures are always presented with a pair of negative words. Pictures of healthy activities are always presented with a pair of positive words. Each picture is presented with a fixed pair of words. Participants will be instructed to select one word to get the most monetary reward. Specifically, in response to each gaming picture, selecting one word will have a 70% chance to get a monetary reward and the other word will have a 30% chance to get a monetary reward. A similar rationale applies to the pictures of healthy activities. The reward setting will help consolidate target associations.Each training session includes 300 times/trials of each type of association, presented in pseudorandom way. The whole training includes 14±5 days. Participants will receive one training session every day.

Locations

Country	Name	City	State
China	Jinan University	Guangdong	Guangzhou
China	South China Normal University	Guangzhou	Guangdong

Sponsors (1)

Lead Sponsor	Collaborator
Jinan University Guangzhou

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	changes in gaming-related compulsive thoughts	The scores of gaming-related compulsive thoughts will be assessed with the Yale-Brown Obsessive-Compulsive Scale modified for internet gaming disorder.	baseline and within 1 day after intervention
Primary	changes in gaming-related compulsive behaviors	The scores of gaming-related compulsive behaviors will be assessed with the Yale-Brown Obsessive-Compulsive Scale modified for internet gaming disorder.	baseline and within 1 day after intervention
Primary	changes in IGD severity	The scores of IGD severity will be assessed with the internet addiction test for internet gaming disorder.	baseline , within one day after intervention, and one month after intervention
Primary	changes in withdrawal symptoms	The scores of withdrawal symptoms will be assessed with the mood and physical symptoms scale.	baseline and within 1 day after intervention
Primary	changes in weekly gaming time	weekly gaming time will be recorded by Software.	baseline and within 1 day after intervention
Primary	changes in craving	Craving will be assessed using a Visual Analog Scale during a cue-reactivity task.	baseline and within 1 day after intervention
Primary	changes in inhibition	Go NoGo task	baseline and within 1 day after intervention
Primary	change of BOLD signals	Task-based fMRI and resting state fMRI.	baseline and within 1 day after intervention
Secondary	changes in risk-taking tendencies	The balloon analogue risk task (BART)	baseline and within 1 day after intervention
Secondary	changes in the quality and patterns of sleep	The scores of the quality and patterns of sleep will be assessed with the Pittsburgh Sleep Quality Index (PSQI).	baseline and within 1 day after intervention
Secondary	changes in the severity of depression	The scores of the severity of depression will be assessed with the Beck Depression Inventory(BDI)	baseline and within 1 day after intervention
Secondary	changes in the severity of anxiety	The scores of the severity of anxiety will be assessed with the Beck Anxiety Inventory (BAI)	baseline and within 1 day after intervention
Secondary	changes in the severity of two emotion regulation strategies, cognitive reappraisal and expressive suppression	The scores of emotion regulation strategies will be assessed with the Emotion Regulation Questionnaire (ERQ)	baseline and within 1 day after intervention