The Observation About the Effects of Internal Carotid Artery Stenosis on Fundus Vessels and the Changes of Fundus Vessels After Interventional Therapy

Internal Carotid Artery Stenosis Clinical Trial

Official title:

The Observation About the Effects of Internal Carotid Artery Stenosis on Fundus Vessels and the Changes of Fundus Vessels After Interventional Therapy

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05260229
• Other study ID #: cuiyanqiluteam
• Status: Recruiting
• Start date: December 12, 2021
• Est. completion date: May 31, 2022

Study information

• Verified date: October 2021
• Source: Qilu Hospital of Shandong University
• Contact: Yan Cui, doctor
• Phone: (+86)18560088136
• Email: cyeleanor[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators plan to collect 30 participants with internal carotid artery stenosis to observed the relationship between the degree of internal carotid artery stenosis and fundus vessels （and blood flow）density before operation, and compared with participants without internal carotid artery stenosis.The fundus blood flow density will be observed after intervention operation in order to see whether the operation is effective to improve the density of fundus vessels and blood flow or not.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30
• Est. completion date: May 31, 2022
• Est. primary completion date: April 30, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 45 Years to 80 Years

Eligibility

Inclusion Criteria:

1. Patients who have been diagnosed with carotid artery stenosis and need surgery;

2. Patients whose vision won't get worse soon;

3. Patients have not had any eye surgeries;

4. Patients with complete profile.

Exclusion Criteria:

1. Patients with severe systemic disease;

2. Patients with poor dioptric stroma;

3. Patients with nystagmus;

4. Patients with incomplete profile.

Related Conditions & MeSH terms

• Carotid Stenosis
• Constriction, Pathologic
• Internal Carotid Artery Stenosis

Locations

Country	Name	City	State
China	Department of ophthalmology and neurology at Qilu Hospital of Shandong University	Jinan	Shandong

Sponsors (1)

Lead Sponsor	Collaborator
Qilu Hospital of Shandong University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The differences of perfusion density in the Forum of the optical coherence tomography angiography(OCTA )of Zeiss Company	The perfusion density differences between the fundus vessels(both the macula area and the optic disc area) on the carotid artery stenosis side and the not-significant narrowing side,or the perfusion density differences between the fundus vessels(both the macula area and the optic disc area) on the carotid artery stenosis side and the side with carotid artery stenosis of different degrees.	2022-01-31
Primary	The differences of perfusion density in the Forum of the optical coherence tomography angiography(OCTA )of Zeiss Company	The perfusion density differences between the fundus vessels on the carotid artery stenosis side and the same side after interventional surgery.	2022-02-14
Primary	The differences of vessel density in the Forum of the optical coherence tomography angiography(OCTA )of Zeiss Company	The vessel density differences between the fundus vessels(both the macula area and the optic disc area) on the carotid artery stenosis side and the not-significant narrowing side,or the vessel density differences between the fundus vessels(both the macula area and the optic disc area) on the carotid artery stenosis side and the side with carotid artery stenosis of different degrees.	2022-01-31
Primary	The differences of vessel density in the Forum of the optical coherence tomography angiography(OCTA )of Zeiss Company	The vessel density differences between the fundus vessels on the carotid artery stenosis side and the same side after interventional surgery.	2022-02-14
Primary	The perimeter and area of the fovea avascular zone(FAZ)in the Forum of the optical coherence tomography angiography(OCTA )of Zeiss Company	The differences between the perimeter and area of the fovea avascular zone(FAZ) of the carotid artery stenosis side before and after interventional surgery.	2022-02-14