Intermittent Hypoxia Clinical Trial
Official title:
Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals
NCT number | NCT05423470 |
Other study ID # | 2018110129 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | May 30, 2019 |
Est. completion date | July 1, 2022 |
Verified date | December 2022 |
Source | University of Texas at Austin |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The objective of the present study is to determine whether intermittent hypoxia protects against ischemia-reperfusion injury in young and older healthy individuals. The investigators hypothesize that intermittent hypoxia will attenuate the reduction in flow-mediated dilation following ischemia-reperfusion injury.
Status | Completed |
Enrollment | 41 |
Est. completion date | July 1, 2022 |
Est. primary completion date | December 30, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: - Men and women aged 18 to 80 years old Exclusion Criteria: - Have high blood pressure (above 130/80 mmHg) - Are smokers - Are pregnant - Have a history of cardiovascular disease, diabetes or lung disease - Are taking medication affecting the cardiovascular system - Carpal tunnel syndrome |
Country | Name | City | State |
---|---|---|---|
United States | The Unviersity of Texas at Austin | Austin | Texas |
Lead Sponsor | Collaborator |
---|---|
University of Texas at Austin |
United States,
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* Note: There are 25 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in endothelial-dependent vasodilation of the brachial artery will be assessed by flow-mediated dilation using an ultrasound machine | Indicator of nitric oxide-dependent endothelial function | Measured before and 15 minutes after an ischemia-reperfusion injury. |
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