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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04741152
Other study ID # 1899898189bf
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 2010
Est. completion date December 2020

Study information

Verified date February 2021
Source Vishnevsky Center of Surgery
Contact n/a
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

The blinded resection avoided in case of pancreatic insulinoma


Description:

Despite of the technique and technology developement there are still a lot of troubles to verify small benign-looking pancreatic NETs. It can be especially important in case of insulinoma. The organic hyperilsulinism and severe hypoglicemia causeb by the insulin/proinsulin - producing lesion can lead to severe complications and evem death. There are some cases of the blinded resections of the pancreas in patients with the "hidden" insulinoma when the tumor can't be revealed during the preoperative diagnostics and intraoperatively. Unfortunately, blind resection do not solve the problem of the hypoglicemia but also cause the specific pancreatic complications.


Recruitment information / eligibility

Status Completed
Enrollment 197
Est. completion date December 2020
Est. primary completion date June 2020
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: The blinded resection of the insulinoma Exclusion Criteria: Other tumors

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
Pancreatic resection
Different pancreatic resections

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Vishnevsky Center of Surgery

Outcome

Type Measure Description Time frame Safety issue
Primary No hidden insulinomas To improve the diagnostics of the tumor before and during the surgery. The "hidden" insulinomas haven't been diagnosed. The frozen section have to be routinely performed. The surgery haven't been finished before the morphologic confirmation of the resected lesion. 2010 June - 2020 June