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NCT00647179 Clinical Trial

Substrate Metabolism and Insulin Sensitivity in Acromegalic Patients Before and After Treatment

Insulin Resistance Clinical Trial

Official title:
Substrate Metabolism and Insulin Sensitivity in Acromegalic Patients Before and After Treatment

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00647179
Other study ID # MM-ISA-20070130
Secondary ID M-20070130
Status Completed
Phase N/A
First received March 26, 2008
Last updated December 22, 2017
Start date February 2008
Est. completion date December 7, 2016

Study information
Verified date December 2017
Source University of Aarhus
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to investigate the effects of chronic elevated growth hormone on metabolism and insulin sensitivity by studying acromegalic patients before and after treatment.

Recruitment information / eligibility
Status Completed
Enrollment 27
Est. completion date December 7, 2016
Est. primary completion date December 7, 2016
Accepts healthy volunteers No
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria:

- Written consent

- Age between 18 and 70

- Recently diagnosed with acromegaly

Exclusion Criteria:

- NYHA 3

- Uncontrolled hypertension

- Known cerebrovascular disease

- Proliferative retinopatia

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Transsphenoidal adenomectomy
Surgery

Locations
Country Name City State
Denmark Department of Endocrinology, Aarhus University Hospital Aarhus C Aarhus

Sponsors (2)
Lead Sponsor Collaborator
University of Aarhus Aarhus University Hospital

Country where clinical trial is conducted

Denmark, 

Outcome
Type Measure Description Time frame Safety issue
Primary Insulin sensitivity Before and after treatment
Secondary QoL, body composition, intrahepatic and intramyocellular fat, substrate metabolism, Glucose tolerance Before and after treatment
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