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Insomnia clinical trials

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NCT ID: NCT03688984 Completed - Insomnia Clinical Trials

Treatment of Insomnia for Adolescents With Mild Traumatic Brain Injury

Start date: September 1, 2016
Phase: N/A
Study type: Interventional

A substantial number of children and adolescents sustain a mild traumatic brain injury (mTBI) each year. Although research supports that the vast majority of youth will recover quickly and return to normal functioning, some adolescents continue to report problems long after the injury. Disturbed sleep, notably trouble with sleep onset and sleep maintenance, is a frequently reported problem in those with slow recovery from a mTBI. Poor sleep is also associated with cognitive complaints, mood disturbance, and lower quality of life. Despite the identification of sleep disturbance as a problem associated with slow recovery, there are very few treatment options. Cognitive-behavioural therapy for insomnia (CBT-I) has shown promise in children and adolescents as an effective treatment for sleep disturbance, although it has yet to be applied to the adolescent mTBI population who also present with sleep problems. The objective of this study is to examine the treatment of sleep disturbance using cognitive-behavioural therapy for insomnia (CBT-I) in those adolescents who have a protracted recovery from their mTBI. This represents a novel treatment option for this patient population and is anticipated to improve outcomes and quality of life.

NCT ID: NCT03688763 Active, not recruiting - Insomnia Clinical Trials

A Pilot Study of Digital Cognitive Behavioral Therapy for Veterans

Start date: February 5, 2018
Phase: N/A
Study type: Interventional

The proposed study is a multiple baseline design pilot study which seeks to evaluate the impact of digitally administered CBT-I, using the Sleepio platform, for the treatment of insomnia disorder among Veterans with co-morbid psychopathology. In addition, information related to acceptability and feasibility of the intervention among a Veteran sample will be obtained.

NCT ID: NCT03683381 Completed - Epilepsy Clinical Trials

App-based Intervention for Treating Insomnia Among Patients With Epilepsy

Start date: September 26, 2018
Phase: N/A
Study type: Interventional

Sleep can affect frequency and occurrence of interictal spikes and occurrence, timing, and threshold of seizure. Epilepsy can worsen sleep architecture and severity of sleep disorders. Thus, a vicious cycle is set. Certain epilepsy syndromes are so intertwined with sleep that they are considered sleep-related epilepsies. Poor sleep in epilepsy is multifactorial and is worsened by poorly controlled seizures. App-delivered intervention has shown promise as a method to overcome health issues; however, the long-term effectiveness has not been proven in epileptic patients with chronic insomnia.

NCT ID: NCT03682185 Completed - Alzheimer Disease Clinical Trials

The Healthy Patterns Sleep Study

Start date: May 1, 2016
Phase: Phase 3
Study type: Interventional

The Healthy Patterns Study intervention is a home-based activity intervention designed to improve symptoms of circadian rhythm disorders (CRD) and quality of life (QOL) in home-dwelling persons with dementia. We will use a randomized two-group parallel design of 200 people with dementia and their caregivers assigned to intervention or attention control groups.

NCT ID: NCT03676491 Completed - Depression Clinical Trials

Music to Improve Sleep Quality in Adults With Depression and Insomnia

MUSTAFI
Start date: May 23, 2018
Phase: N/A
Study type: Interventional

Insomnia is a common sleep disorder for patients with depression. This has a major impact on the quality of life for the individual. The aim is to investigate, whether music intervention is effective in 1. improving sleep quality, 2. reducing symptoms of depression and 3. improving quality of life Participants use a sound pillow and selected music in the The Music Star app at home as a sleep aid in 4 weeks.

NCT ID: NCT03673397 Completed - Depression Clinical Trials

The Acute Effect of Aerobic Exercise on Sleep in Patients With Depression

EASED
Start date: September 24, 2018
Phase: N/A
Study type: Interventional

The aim of this trial is to investigate the effects of a single bout of aerobic exercise on sleep in patients with depression.

NCT ID: NCT03668041 Recruiting - Insomnia Clinical Trials

National Adaptive Trial for PTSD Related Insomnia

NAP
Start date: February 25, 2021
Phase: Phase 3
Study type: Interventional

Many Veterans with posttraumatic stress disorder (PTSD) have trouble sleeping or have frequent nightmares. So far, no medication has been approved for treatment of insomnia in PTSD. The purpose of this research study is to find out if taking medications called trazodone or eszopiclone can help decrease symptoms of insomnia in patients with PTSD. PTSD is a form of intense anxiety which sometimes results from severe trauma. Symptoms may include nightmares, flashbacks, troublesome memories, difficulty sleeping, poor concentration, irritability, anger, and emotional withdrawal. Insomnia is a disorder that can make it hard to fall sleep, stay asleep or cause a person to wake up too early and not be able to fall back to sleep.

NCT ID: NCT03665337 Recruiting - Insomnia Clinical Trials

The Reducing Risk Study

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

The present study will test an innovative mobile health adaptation of a behavioral intervention that improves sleep and mental health concerns among adolescents.

NCT ID: NCT03649958 Active, not recruiting - Insomnia Clinical Trials

Neurotechnology Following Traumatic Brain Injury

Cereset
Start date: August 28, 2018
Phase: N/A
Study type: Interventional

This two-part study seeks to improve symptoms such as pain and sleep problems after concussion, or mild traumatic brain injury (mTBI). Study I evaluates symptoms of mTBI through a series of 10 office sessions in which musical tones are echoed, or mirrored back in real time, to reflect one's own brain activity. Those who take part in the study will be randomly assigned to receive either tones that are based on their brain activity/brainwaves, or random tones. Study II evaluates symptoms of mTBI through either 10 office sessions of the same acoustic stimulation linked to brain activity/brainwaves as Study I compared to 5 office sessions of acoustic stimulation plus intermittent very low level electrical stimulation of the scalp linked to brain activity.

NCT ID: NCT03636880 Completed - Depression Clinical Trials

Heart Failure Insomnia Treatment Study

H-FITS
Start date: February 24, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to compare a short, behavioral treatment for insomnia with sleep monitoring to determine whether these approaches are effective in reducing insomnia and improving sleep quality among patients with heart failure (HF). This study will also examine the relationship between insomnia and cognitive functioning in HF and the effects of the behavioral treatment on cognitive functioning, self-care, distress, HF symptoms, and functional status. Participants will be randomly assigned to four-sessions of a behavioral treatment (Brief Behavioral Treatment for Insomnia; BBTI) or sleep monitoring.