A Study to Determine the Abuse Potential of Single Oral Doses of Lemborexant Compared to Zolpidem, Suvorexant and Placebo in Healthy, Non-Dependent, Recreational Sedative Users

Insomnia Disorders Clinical Trial

Official title: A Randomized, Double-Blind, 6-Way Crossover Study to Determine the Abuse Potential of Single Oral Doses of Lemborexant Compared to Zolpidem, Suvorexant and Placebo in Healthy, Non-Dependent, Recreational Sedative Users

Status Completed

Clinical Trial Summary

The primary purpose of this study is to evaluate the abuse potential of lemborexant (E2006) in comparison to placebo and 2 controls with known abuse potential (ie, zolpidem and suvorexant) with similar indications (zolpidem and suvorexant) or mechanisms of action (suvorexant).

Clinical Trial Description

This is a single-center, single oral dose, randomized, double-blind, placebo-controlled, 6-way crossover study in healthy, non-dependent recreational sedative users. ;

Related Conditions & MeSH terms

• Insomnia Disorders
• Sleep Initiation and Maintenance Disorders

• NCT number: NCT03158025
• Study type: Interventional
• Source: Eisai Inc.
• Status: Completed
• Phase: Phase 1
• Start date: April 19, 2017
• Completion date: July 4, 2018