Influenza Clinical Trial
— CMVfluOfficial title:
A Phase IV, Single Group Study to Evaluate the Immune Response to Licensed Seasonal Influenza Vaccine and Relationship of This to Cytomegalovirus-associated Immunosenescence in UK Older Adults Aged 50-80 Years
Verified date | February 2008 |
Source | Public Health England |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The study is being undertaken to evaluate responses to seasonal influenza vaccine in older adults with respect to their CMV status. CMV is cytomegalovirus and is an organism that infects many people, but does not usually cause disease in the individual unless they are immunocompromised i.e. their immune system is not working well such as in the case of HIV infection. CMV is believed to have infected up to 80% of individuals in the age group we will be looking at in our study and we are interested in whether this infection affects their responses to vaccination.
Status | Completed |
Enrollment | 100 |
Est. completion date | September 2007 |
Est. primary completion date | |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 50 Years to 80 Years |
Eligibility |
Inclusion Criteria: - No contraindications to vaccination as specified in the "Green Book" - Immunisation Against Infectious Disease, HMSO. - Written informed consent obtained - Subject aged no less than 50 years 0 days and no older than 79 years and 364 days at enrollment. |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Hertfordshire Primary Care Trust | Stevenage |
Lead Sponsor | Collaborator |
---|---|
Public Health England | Royal Free and University College Medical School |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Response to influenza vaccination (HI) |
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