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Influenza, Human clinical trials

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NCT ID: NCT01130636 Completed - Influenza Clinical Trials

Observational Study on the Pharmacokinetics of Oseltamivir in the Treatment of Influenza During Lactation

Start date: June 2010
Phase: Phase 4
Study type: Interventional

The main purpose of this study is to assess the potential exposure of neonates to oseltamivir during lactation by examining oseltamivir concentrations in maternal blood, urine, and breast milk in breastfeeding women who are treated with oseltamivir, an anti-flu medication.

NCT ID: NCT01123954 Completed - Seasonal Influenza Clinical Trials

Evaluating the Safeness of Trivalent Subunit Inactivated Influenza Vaccines in Preventing Flu on Vietnamese Volunteers

Start date: January 2010
Phase: Phase 2
Study type: Interventional

The present study will evaluate the safety in healthy people aged 1- 45 years (male and female) after single intramuscular (IM) dose of trivalent subunit inactivated influenza vaccine till the 30-days follow-up period.

NCT ID: NCT01121822 Completed - Influenza Clinical Trials

Immunogenicity and Safety of a Vaccine Against Influenza (2010-2011 Northern Hemisphere Season, Intramuscular Route)

Start date: May 2010
Phase: Phase 3
Study type: Interventional

The aim of this study is to evaluate the new formulation of the influenza vaccine for the 2010-2011 Northern Hemisphere (NH) season in terms of immunogenicity and safety in the corresponding population and to check its compliance with the Committee for Proprietary Medicinal Products (CPMP) Note for Guidance (NfG) CPMP/BWP/214/96 Objectives: - To evaluate the compliance, in terms of immunogenicity, of the influenza vaccine (split virion, inactivated) NH 2010-2011 formulation with the requirements of the Committee for Proprietary Medicinal Products (CPMP) Note for Guidance (NfG) CPMP/BWP/214/96 in both age groups - To describe the safety of the influenza vaccine (split virion, inactivated) NH 2010-2011 formulation in both age groups

NCT ID: NCT01114620 Completed - Influenza Clinical Trials

Study of GSK Biologicals' Influenza Vaccine Arepanrix™ in Japanese Adults 65 Years of Age or Older

Start date: May 17, 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to comply with the post marketing condition to the exceptional approval of Arepanrix™ in Japan and to assess the immunogenicity and safety of GSK Biologicals' H1N1 influenza vaccine healthy Japanese adults 65 years of age or older.

NCT ID: NCT01111968 Completed - Influenza Clinical Trials

Evaluation of Pandemic Influenza A (H1N1)Candidate Vaccines

Start date: January 2010
Phase: Phase 1
Study type: Interventional

This is a prospective phase I study to evaluate the safety, tolerability and immunogenicity of nine adjuvanted candidate vaccines against pandemic influenza A (H1N1) virus.

NCT ID: NCT01107262 Completed - Virus Diseases Clinical Trials

Avian Influenza Studies In Lebanon

Start date: July 2009
Phase: N/A
Study type: Observational

The highly pathogenic avian influenza (HPAI) H5N1 virus arrived in the Middle East in 2005 and has since established itself in local domestic birds and is now considered endemic in several Middle Eastern countries.Few studies indicate the presence of low pathogenicity avian influenza (LPAI) viruses of the H9 type among Lebanese poultry and wild birds. These studies also provide some evidence suggesting that humans exposed to these sick birds are showing elevated antibody titers against these LPAI H9 viruses. This study will focus on the following objectives: - To determine the seroprevalence of AI in poultry-exposed and non-exposed human populations. - To identify risk factors associated with AI infections in occupationally-exposed poultry workers. - To conduct nation-wide cross-sectional surveillance for AI viruses among domestic birds in low biosecurity farms and backyard flocks.

NCT ID: NCT01106196 Completed - Influenza Clinical Trials

The Role of Influenza as a Trigger for Acute Myocardial Infarction: a CALIBER Study

Start date: April 2010
Phase: N/A
Study type: Observational

The purpose of this study is to examine the incidence of acute myocardial infarction (MI) occurring after an influenza-like illness using linked primary care and disease registry databases.

NCT ID: NCT01100294 Completed - Influenza Clinical Trials

Tolerability and Safety Study of FLUVAL P Monovalent Influenza Vaccine in Children

Start date: September 2009
Phase: N/A
Study type: Interventional

To determine the tolerability and safety of FLUVAL P monovalent influenza vaccine in children.

NCT ID: NCT01098786 Completed - Clinical trials for Swine-Origin Influenza A H1N1 Virus

Drug Use Investigation for Cell-culture Derived Influenza A (H1N1) Emulsion HA Vaccine

Start date: February 2010
Phase: N/A
Study type: Observational

This is to evaluate safety of cell-derived A/H1N1 influenza HA vaccine in healthy Japanese subjects.

NCT ID: NCT01096056 Completed - Influenza Clinical Trials

Trial to Evaluate the Safety and the Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2186877A in Healthy Children

Start date: April 5, 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and immunogenicity of GlaxoSmithKline Biologicals' influenza vaccine GSK2186877A in healthy children 6 to 35 months of age. This Protocol Posting has been updated following Amendment 1 of the Protocol, Jun 2010. The impacted sections are study design, outcome measures, intervention sections and number of subjects.